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作 者:任汉阳[1] 王玉英 张瑜[1] 薛春苗[3] 任慧玲[1] 李寒冰[1]
机构地区:[1]河南中医学院药学院,河南郑州450008 [2]海缘药业股份有限公司,江苏连云港222000 [3]山西中医学院,山西太原030000
出 处:《山东中医杂志》2006年第3期200-202,共3页Shandong Journal of Traditional Chinese Medicine
基 金:河南省科技攻关项目(编号:0224630121)
摘 要:目的:观察黄精粗多糖(PSP)对家蚕寿命的影响。方法:以家蚕为实验对象,取龄期相同,生长整齐的三眠蚕随机分为空白对照组,PSP高(浓度为2%)、中(浓度为1%)、低(浓度为0.5%)剂量组,维生素E(浓度为0.5%)阳性对照组。使用喷雾法将药液喷于新鲜桑叶上喂食,4龄期内喂药3次,5龄期内喂药6次。结果:PSP高、中、低浓度的水溶液,可不同程度地延长家蚕幼虫期、雌蛹期、雌蛾期和全生存期的时间,同时有减轻幼虫体质量、延长耐饥饿时间的作用,PSP对上述指标的改变与维生素E的作用相当。结论:PSP是黄精抗衰老作用的重要活性成分,具有进一步研究开发的价值。Objective. Study the influence of polygonatum sibiricum polysaccharide( PSP)on the life spans of silkworm. Methods, The silkworms were used as experimental objects which were hatched at the same, time and have got through their dormant period thrice. They were divided into 5 groups.control grouP, high(2%) PSP dose group,middle(l%) dose group,low(0.5%) dose group and vitamine E(0.5%) applied group. The liquid medicine were sprayed on the surface of fresh leaves of mulberry for each group which were used as silkworms' feed. The medicine were provided 3 times after the fourth do.rmant period of the silkworms and 6 times after the fifth dormant period of the silkworms. Results: The high,middle/ and lowPSP dose can prolong the silkworms' life span of larva-period,female chrysalis-period and female. moth-period to different extent, can lighten the weight of larva silkworm, strengthen the resistivity of starvation of five age larva silkworm. The effect of PSP is the same as vitamine E. Conclusion. PSP is the important anti-aging active site of polygonatum sibiricum redoute. It is worth studying further.
分 类 号:R282.710.5[医药卫生—中药学]
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