小儿感冒舒颗粒中荆芥挥发油β-环糊精包合的工艺研究  

Study on the Process of Inclusion Volatile Oil of Herba Schizonepetae with β-cyclodextrin from Xiao'er Ganmaoshu Granule

作　　者：赵开军 濮存海 关志宇 

机构地区：[1]南京中山制药厂技术中心,江苏南京210012

出　　处：《中药材》2006年第2期181-184,共4页Journal of Chinese Medicinal Materials

摘　　要：目的:研究小儿感冒舒颗粒中β-环糊精包合荆芥挥发油的最佳工艺。方法:利用正交实验法,考察β-环糊精与挥发油的配比、包合温度、包合时间3个因素对挥发油利用率、包合物含油率的影响。结果:最佳包合工艺为:荆芥油:β-环糊精(1m l∶10 g)、包合温度60℃、包合时间3 h。结论:该工艺简便、易行,可用于大生产。Objective： To study optimum inclusion process conditioo for volatile oil with β-cyclorlcxtfin（β-CD）. Methods： The optimum preparation condition were investigated by orthogonal design. The irrfluence of utilization β-CD alrd oil, inclusion temperature and time were studied to determin the utilization ratio of w^latile oil and oil-bearing rate. Results： The optimum preparation conditions were established as： volatile oil： β-CD was 1： 10, tire inclusion temperature was 60℃ and inclusion time was 3h. Conclusion： The method is convenient and can bc used for mass production.

关 键 词：荆芥挥发油 Β-环糊精包合物 正交实验设计 

分 类 号：R283.6[医药卫生—中药学]