Duplication and divergent evolution of the CHS and CHS-like genes in the chalcone synthase(CHS)superfamily  

作　　者：YANG Ji GU Hongya 

机构地区：[1]College of Life Sciences, Peking University, Beijing 100871, China

出　　处：《Chinese Science Bulletin》2006年第5期505-509,共5页

基　　金：supported by the National Key Project for Basic Research(973)(Grant No.2003CB715904);the National Natural Science Foundation of China(Grant No.39830020).

摘　　要：The enzymes of the CHS-superfamily are responsible for biosynthesis of a wide range of natural products in plants. They are important for flower pigmentation, protection against UV light and defense against phytopathogens. Many plants were found to contain multiple copies of CHS genes. This review summarizes the recent progress in the studies of the CHS-superfamily, focusing on the duplication and divergent evolution of the CHS and CHS-like genes. Comparative analyses of gene structure, ex- pression patterns and catalytic properties revealed extensive differentiation in both regulation and func- tion among duplicate CHS genes. It is also proposed that the CHS-like enzymes in the CHS-superfamily evolved from CHS at different times in various or- ganisms. The CHS-superfamily thus offers a valuable model to study the rates and patterns of sequence divergence between duplicate genes.The enzymes of the CHS-superfamily are responsible for biosynthesis of a wide range of natural products in plants. They are important for flower pigmentation, protection against UV light and defense against phytopathogens. Many plants were found to contain multiple copies of CHS genes. This review summarizes the recent progress in the studies of the CHS-superfamily, focusing on the duplication and divergent evolution of the CHS and CHS-like genes. Comparative analyses of gene structure, expression patterns and catalytic properties revealed extensive differentiation in both regulation and function among duplicate CHS genes. It is also proposed that the CHS-like enzymes in the CHS-superfamily evolved from CHS at different times in various organisms. The CHS-superfamily thus offers a valuable model to study the rates and patterns of sequence divergence between duplicate genes.

关 键 词：苯基苯乙烯酮合酶 基因复制 分裂演进 CHS基因 植物生物化学 

分 类 号：Q946.5[生物学—植物学]