芳氧苯氧丙酸类除草剂在两种手性柱上的对映体分离  

Enantioseparation of Four Aryloxyphenoxypropionic Acid Herbicides by High Performance Liquid Chromatogrpahy on Cellulose Tris(3,5-dimethylphenylcarbamate and(S,S)-Whelk-O 1

作　　者：潘春秀[1] 吴清洲[1] 沈报春[1] 张雪君[1] 张大同[1] 徐秀珠[1] 

机构地区：[1]浙江大学化学系

出　　处：《分析化学》2006年第2期159-164,共6页Chinese Journal of Analytical Chemistry

基　　金：浙江省科技计划项目(No.2004c33050);分析测试基金(No.03111)资助

摘　　要：在自制的涂敷型纤维素三(3,5-二甲基苯基氨基甲酸酯)(CDMPC)手性柱和P irkle型(S,S)-W helk-O 1手性柱上对禾草灵,吡氟禾草灵,喹禾灵,噁唑禾草灵4种芳氧苯氧丙酸类除草剂进行了对映体分离。分别考察了在流动相正己烷中,极性醇类添加剂种类、和浓度以及溶质的结构因素对手性分离的影响,探讨了溶质在两种手性柱上的手性识别的机理。结果显示:噁唑禾草灵在(S,S)-W helk-O 1上获得了较好的分离,其它时3种溶质均在CDMPC上获得了较好的分离,各溶质都达到基线分离。两种手性柱的手性识别机理不同,溶质和固定相的结构是手性识别的关键。A method of enantioseparation of diclofop, fluazifop, quizalofop-P and fenoxaprop using self-prepared cellulose derivative cellulose tris （3,5-dimethylphenylcarbanate） （ CDMPC ） and （ S, S） -Whelk-O 1 columns was repotted in this study. The influence of the mobile phase composition and solute structure on the chiral separation was studied. And their chiral recognition mechanism was discussed. The experiment results showed that fenoxaprop is best separated on （S,S）-Whelk-O 1, while the other three solutes are well separated on CDMPC. It was concluded the chiral recognition mechanisms of these acids on CDMPC and （S, S）- Whelk-O 1 are different from each other. And the structure of solute and cellulose tris （3,5-dimethylphenyl- carbanate） plays a key role in the chiral recognition.

关 键 词：对映体分离 芳氧丙酸类除草剂 纤维素三(3 5.二甲基苯基氨基甲酸酯) (S  S)-Whelk-O 1 

分 类 号：TQ457.1[化学工程—农药化工]