无排卵月经周期血及腹腔液中β－EP，L－EK，SS的含量变化  

THE CONTENTS OF β-EP,L-EK,AND SS IN PLASMO AND PERITONEAL FLUID DURING ANOVULOMENORRHEA

作　　者：方爱华[1] 张令浩[1] 王成海[1] 

机构地区：[1]第二军医大学长征医院妇产科

出　　处：《上海医学》1996年第1期11-14,共4页Shanghai Medical Journal

摘　　要：本文用放射免疫法测定了有排卵月经周期及无排卵月经周期各２４例妇女的血浆及腹腔液中β－内啡肽（β－ＥＮ，亮氨酸脑啡肽（Ｌ－ＥＫ）和生长抑素（ＳＳ）的含量。结果显示：无排卵月经周期的妇女ＬＨ峰值前后血浆、腹腔液β－ＥＰ含量及腹腔液中Ｌ－ＥＫ含量均显著高于有排卵月经周期妇女，无排卵月经周期中期的β－ＥＰ含量显著升高提示可能参与调控ＬＨ的分泌，抑制排卵前ＬＨ峰，阻断排卵，本文为神经肽类药物以抑制ＬＨ峰，阻断排卵，控制生育，提供一定的理论参数。he contents of β-endorphin(β-EP),Leucine-enkephalin(L-EK)and somatostation(SS)in plasma and peritoneal fluid were determined by radioimmunoassay in 24 casses ofwomen with anovular cycle, controlled by 24 cases of women with ovular cvcle. Resultsshowed that the contents of β-EP and L-EK at LH surge in plasmaand peritoneal fluid inwomen with anovular cycle were significantly higher than those women with ovular cycle.The increased β-EP at mid-cycle in women with anovulae cycle indicated that B-EP may par-ticipate in the regulation of LH secretion,inhibit LH surge before ovulation,then break offovulation. This will contribute to theoretical basis for neuroendorphin as drugs to inhibit LHsurge,break off ovulation and control fertility

关 键 词：Β-内啡肽 亮氨酸脑啡肽 生长抑素 无排卵月经 

分 类 号：R711.602[医药卫生—妇产科学]