清源调脂胶囊治疗酒精性肝病临床效果评价  

Clinical effects of Qingyuan Tiaozhi capsule on alcoholic liver disease

作　　者：林爱清[1] 李文彪[2] 张瑞芬[1] 陈予[2] 

机构地区：[1]包头医学院第一附属医院,内蒙古包头014010 [2]包头医学院中蒙医药研究所

出　　处：《中西医结合肝病杂志》2006年第1期11-13,共3页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：包头市科技局卫生科研基金资助(N0.2002G242-21)

摘　　要：目的:评价清源调脂胶囊治疗酒精性肝病的效果。方法:60例酒精性肝病患者随机分为两组,治疗组给予清源调脂胶囊两粒,3次/d,口服。对照组仅口服普通保肝药物。治疗结束后化验肝功能、血脂,采用彩超探查肝脏。结果:治疗结束后治疗组总有效率93.3%,对照组总有效率73.3%,两组总有效率比较差异有显著性意义(P<0.01)。治疗组患者治疗后血清胆固醇(TCho)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)与用药前比较差异有显著性意义(P<0.01),与对照组治疗后比较差异有显著性意义。治疗组肝功能指标与治疗前比较差异有显著性意义,与对照组治疗后比较差异有显著性意义。结论:清源调脂胶囊可以缓解酒精性肝病患者临床症状,改善肝功能及肝脏影像学变化,降低血脂,临床疗效肯定。Objective：To evaluate the effects of Qingyuamiaozhi capsule on alcoholic liver disease. Methods： Sixty patients with alcoholic liver disease were divided at random into two groups. Therapeutic group was treated with two capsules of Qingyuantiaozhi capsule orally three times per day, control group was treated with general medicine to protecting the liver. After the period of treatment, all the patients performed blood test of liver function and cholesterol and triglyceride low density ilpoprotein-C, as well detecting the liver with colour ultrasound.Results. Total effective ratio of therapeutic and control group was 93.3 % and 73.3 % which were significantly difference in two groups （P 〈 0.01 ） . There was also significantly difference in the two groups with the liver funetiion and cholesterol and triglycerin, and low density lipoprotein-C （p 〈 0.01） .Conclusion： Qingyuantiaozhi capsule has a significant effect to improve the patients＇clinical syndromes and liver functiions, even it change the patients＇ liver imagining in ultrasound but to decrease patients＇ blood-fat.

关 键 词：酒精性肝病 清源调脂胶囊/治疗应用 病例对照研究 

分 类 号：R259[医药卫生—中西医结合]