终末期肾衰患者的精神症状与生活质量的相关分析  

Association of psychiatric symptoms and quality of life in end-stage renal disease patients

作　　者：彭涛[1] 胡昭[1] 刘希会[2] 白凤[1] 冯英[1] 强玲[1] 丛敏[1] 朱运锋[1] 唐利军[1] 

机构地区：[1]山东大学齐鲁医院肾内科,山东济南250012 [2]临沂市人民医院肾内科,山东临沂276003

出　　处：《山东大学学报（医学版）》2006年第1期102-105,共4页Journal of Shandong University:Health Sciences

摘　　要：目的:探讨终末期肾衰患者焦虑、抑郁症状与生活质量的关系。方法:采用健康相关生活质量量表(SF-36)调查57例终末期肾衰患者生活质量,SF-36包括8个纬度,体能(PCS)和精神(MCS)两方面总分;分别用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评估患者抑郁、焦虑症状,并将其分为抑郁组与非抑郁组、焦虑组与非焦虑组,比较生活质量组间差异。结果:抑郁症状的发生率为38.6%,焦虑症状的发生率为54.4%。抑郁、焦虑评分与生活质量8个纬度中7项呈负相关,与PCS和MCS呈负相关(P<0.05)。抑郁组、焦虑组以及二者共存组的生活质量明显低于无相应精神症状组患者(P<0.05)。结论:终末期肾衰患者焦虑症状和抑郁症状发生率较高,与患者生活质量相关。有效改善患者精神症状可能是提高患者生活质量途径之一。Objective： To investigate the association of psychiatric symptoms （anxiety and depression） and quality of life in end-stage renal disease （ESRD） patients. Methods： Quality of life was evaluated in a sample of 57 ESRD patients by SF-36 questionnaire included eight scales, which were tested for a physical component summary （PCS） and a mental component summary （MCS） score for each patient. Depression and anxiety were estimated by Hamilton Depression Rating Scale （HAMD） and Hamilton Anxiety Rating Scale （HAMA） respectively. Results： Despite 38.6% patients with depression and 54.4% with anxiety, depression and anxiety scores were negatively correlated with 7 out of 8 scales of SF-36 questionnaire, with PCS andMCS scores, whereas. Quality of lite scores in the depression group, me anxtiety group and the anxiely depression co-morbid group were lower than those without corresponding psychiatric symptoms （P〈0.05）o Conclusion： This study has demonstrated that depression and anxiety are commonly encountered in ESRD patients, which may be risk factors of quality of life, suggesting that reducing psychiatric symptoms effectively may be a path way to improve quality of life in ESRD patients.

关 键 词：心理学 临床 肾衰竭 晚期 断面研究 生活质量 抑郁 焦虑 

分 类 号：R692[医药卫生—泌尿科学]