南京地区人群血清B_f表型分布及基因频率的调查  

An Investigation on the Distribution of Properdin Factor B Phenotype Frequencies in Nanjing Area

作　　者：达建[1] 周明[1] 

机构地区：[1]南京医科大学法医学教研室,南京210029

出　　处：《南京医科大学学报（自然科学版）》1996年第1期43-44,53,共3页Journal of Nanjing Medical University(Natural Sciences)

摘　　要：采用高压琼脂糖凝胶电泳方法及免疫固定技术,对南京地区人群血清 B_f 表型分布及基因频率进行了调查。通过对110名健康者凋查,结果 B_f表型分布是:SS 型82人,FS 型25人,FF型3人;基因频率为 B_f~=0.86,B_f=0.14。本文为南京地区群体遗传学提供了数据,以供法医学个人识别及亲权鉴定的开展做参考。Using agarose gel high-Voltage electrophoresis followed by immunofixation,the poly- morphism of B_f was determined in 110 healthy human sera in Nanjing.The distribution of B_f pheno- types observed was:SS:82,FS:25,FF:3.Their allele frequencies were:B_f^F=0.14,B_f^S= 0.86.The distribution of B_f phenotypes was in good agreement with that of the Hardy-Weinberg law.

关 键 词：血清 Bf表型 补体 备解素因子 基因频率 南京 

分 类 号：R392.11[医药卫生—免疫学] 43－44[医药卫生—基础医学] 53