HZSM-5型分子筛催化合成2-乙酰噻吩  

Synthesis of 2-acetylthiophene by HZSM-5 zeolite catalyst

作　　者：刘荣杏[1] 佘红梅[1] 张洪林[1] 张连红[1] 蒋林时[1] 许维相[1] 

机构地区：[1]辽宁石油化工大学石油化工学院,辽宁抚顺113001

出　　处：《化工科技》2006年第1期35-38,共4页Science & Technology in Chemical Industry

基　　金：抚顺市科技攻关产业化项目(20052517)

摘　　要：用固体酸催化剂HZSM-5型分子筛代替液体磷酸催化合成2-乙酰噻吩,探讨了反应时间、反应温度、催化剂质量对该反应的影响。采用正交实验法优化的工艺条件是:反应温度为95℃,反应时间为2.5 h,催化剂质量为2.5 g(约占原料质量的3.5%)。最优工艺条件下2-乙酰噻吩的收率为90.60%。产物通过色谱-质谱联用仪分析可知:产品2-乙酰噻吩的质量分数约为98.28%,副产物主要是少量的3-乙酰噻吩。该实验中,固体催化剂可以回收、再生和重复使用,给出的收率几乎与新鲜的催化剂相同。The synthesis of 2-acetylthiophene by using HZSM-5 zeolite was reported, the effects of the amount of the catalyst used, reaction temperature and reaction time were investigated. The preferred reaction conditions given by orthogonal test are：the amount of the catalyst used is 2,5 g（the percentage of material mass is about 3.5% ）, reaction temperature 95℃ and reaction time 2.5 h. Under such conditions, the yield of 2-acetylthiophene is 89.41%. The product is determined by GS-MS and the content is about 98.03 %. The by-product is a little 3-acetylthiophene. The catalyst used here can be recovered, regenerated and reused to give almost the same yield of 2-acetylthiophene as that given by the fresh HZSM-5 zeolite.

关 键 词：2-乙酰噻吩 HZSM-5型分子筛 噻吩 中间体 

分 类 号：TQ251.2[化学工程—有机化工]