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作 者:陈欢[1] 胡云建[2] 毛永辉[2] 刘建社[1]
机构地区:[1]华中科技大学同济医学院附属协和医院,湖北武汉430022 [2]卫生部北京医院,北京100730
出 处:《中华医院感染学杂志》2006年第3期345-347,共3页Chinese Journal of Nosocomiology
摘 要:目的 调查了解2004年尿路感染病原菌的分布及耐药情况,为临床提供可靠的诊断和治疗依据。方法 对2004年1月1日~2004年12月31日间,北京医院住院及门诊患者1007份尿培养标本及其分离出的632株细菌进行鉴定和耐药分析。结果 2004年尿路感染菌株以大肠埃希菌为主,占38.29%;其次为肠球菌属(18.67%)、念珠菌属(17.41%)、链球菌属(8.07%)、变形菌属(3.4%)、葡萄球菌属(3.95%)、铜绿假单胞菌(3.17%)及肺炎克雷伯菌(2.37%);肠杆菌科细菌对亚胺培南保持100%敏感;呋喃妥因和万古霉素对革兰阳性球菌敏感率较高;真菌感染的发生率较2001年有明显上升趋势。结论 2004年尿路感染的主要致病菌仍是肠杆菌属,并以大肠埃希氏菌为主;真菌感染旱明显上升趋势。应高度重视。OBJECTIVE To investigate the bacteria distribution and antibiotic resistance in urinary tract infection in 2004. METHODS During Jan 1st 2004 to Dec 31st 2004, 1007 urine specimens were collected from inpatient and outpatient departments of Beijing Hospital. Totally 632 strains of pathogens were identified and the drug resistance was performed. RESULTS Among pathogens of urinary tract infection in 2004, Escherichia coli rated the first (38. 29%), followed by Enterococcus (18.67%), fungi (17. 41%), Streptococcus (8. 07%), Proteus (3.4%), Staphylococcus (3.95 %), Pseudomonas aeruginosa (3.17 %) and Klebsiella pneumoniae (2.37 %). Enterobacteriaceae were sensitive to imipenem (100%). G^+ cocci were sensitive to nitrofurantoin and vancomycin (nearly to 100%). Compared to pathogens of UTI in 2001, fungi showed obviously increasing trend. CONCLUSIONS In 2004, Enterobaeteriaeeae (mostly E. coli) are the major pathogens in urinary tract infection. Fungi infection in urinary tract has an obviously increasing tendency and should be carefully treated.
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