基因组“k字”频数普适关系的研究  

Research on the Universality of k-mer Frequency Distribution in Genomes

作　　者：李培芳[1] 贾晓超[1] 李宏 罗辽复[1] 

机构地区：[1]内蒙古大学理工学院物理系,呼和浩特010021

出　　处：《内蒙古大学学报（自然科学版）》2006年第2期153-159,共7页Journal of Inner Mongolia University：Natural Science Edition

基　　金：国家自然基金项目(90103030)

摘　　要：寻找物种基因组中k-m er频数分布的特征,对几个典型物种的基因组序列进行了统计分析.区分“字”域和“频数”域,运用两种求信息熵的方法Shannon信息熵和F isher信息熵,定义了五种k-m er频数的泛函.发现对于每一物种,由Shannon信息熵定义的四种泛函与k之间都具有很好的线性关系,并且这种线性关系在所研究的物种间具有普适性.To find the character of the distribution of k-mer frequency in genome, several genomes of typical species are statistically studied. Considering the difference between word domain and frequency domain, using Shannon information and Fisher information respectively, five types of functional of k-mer frequency are defined. The results showed good linear relation existing in each species for four functionals deduced from Shannon information. Moreover,these linear relations are basically universal among the studied species.

关 键 词：基因组 k-mer 频数 信息熵 

分 类 号：Q61[生物学—生物物理学]