变应性疾病患者血清过敏原及总IgE实验分析  

Analysis of serum allergen and total IgE of patients with allergil disease

作　　者：丁黎[1] 徐平[1] 郭静[1] 安阳[1] 贾惠临[1] 

机构地区：[1]宁夏自治区人民医院,宁夏银川750021

出　　处：《宁夏医学杂志》2006年第3期174-176,共3页Ningxia Medical Journal

摘　　要：目的了解临床常见的变态反应性疾病特异性过敏原及血清总IgE水平变化。方法采用酶免疫分析法(ELISA)对112例6种常见变态反应性疾病血清过敏原及总IgE水平进行了检测。结果112例变态反应性疾病患者中吸入组过敏原以家尘为最高,其后依次为尘螨、粉螨,菊花、玫瑰、蒲公英,艾蒿、豚草、车前草,多价霉菌,狗猫毛、皮屑,柳树、榆树;食入组过敏原以海鱼为最高,其后依次为鲜贝、龙虾,虾、蟹,牛、羊、猪肉,牛奶,蛋白、蛋黄,玉米、小麦;血清总IgE以异位性皮炎、荨麻疹、过敏性鼻炎、湿疹为最高,阳性率分别为75%、66.7%、62.5%、60.86%。结论血清过敏原及总IgE酶免疫分析可以帮助临床合理寻找相应过敏原,为变态反应性疾病的预防、诊断和治疗提供依据。Objective To investigate the specific clinic allergen and serum immunoglobulin E（IgE） levels in 112 patients with common allergic disease. Methods Enzyme immuncassay method was sed to detect the specific allergen and total serum IgE level. Results The dermatophagoides pteronysinus（53/112） was the most common allergen in inhalation group in 112 patients with allergic disease, dust mite（43/112）was the next, then was mum, rose, dandelion（31/112）, artenisia, plantain（22/112）, polyvalent fungus（17/112）, dogly, feline scurf（15/112）, osier, elm（11/112） ;while in food group, the most conanon allergen was oceanic fish（25/112）, then was fresh and tender shellfish, langouste（20/112） , shrimp, crab（15/112）, mutton, beef and pork（15/112）, milk（13/112）, egg white, vitellus（8/112）, mealie, wheat（3/ll2）.Total IgE level of patients with atopie dermatitis, urticaria, irritability coryza, eczema was the highest in turn, the positive rotes were 75 %, 66.7 %, 62.5 %, 60.86 %. Conclusion Enzyme immunoassay method can help us to find relevant allergen and provide foundation of the prevention and treatment of allergic disease.

关 键 词：变态反应性疾病 过敏原 IGE 酶免疫分析法 

分 类 号：R593.2[医药卫生—内科学]