安徽省43771例围产儿出生缺陷流行病学监测  

SURVEILLIANCE OF 43771 PERINATES WITH BIRTH DEFECTS IN ANHUI PROVINCE

作　　者：居正华[1] 杜力晟[1] 周占伟[1] 李涤臣[2] 陶真[3] 吴明艳[4] 陈玉荣[4] 翟惠兰 王玲[4] 余茵[4] 

机构地区：[1]蚌埠医学院流行病学教研室 [2]蚌埠医学院病理解剖学教研室 [3]蚌埠医学院附院肿痛研究室 [4]安徽省卫生厅妇幼处

出　　处：《蚌埠医学院学报》1990年第4期266-269,共4页Journal of Bengbu Medical College

摘　　要：本文报道安徽省1986年10月1日～1987年9月30日期间我省29所医院围产儿出生缺陷监测结果。43771名围产儿中,出生缺陷467例,发生率10.67‰;围产儿死亡1600例,死亡率36.55‰。两组性别间均无显著性差异(P>0.05)。81种畸形前五位依次为脑积水、无脑儿、唇腭裂、多指(趾)与足内(外)翻。农村出生缺陷发生率(16.35‰)高于城市(7.37‰),两者有显著性差异(P<0.01)。皖北地区神经管畸形居首位;皖南、皖中则以肢体畸形多见。木文初步探讨了出生缺陷与父母血缘、母亲文化程度低、年龄<20或>35岁、多孕次、产次、双胎等因素的关系。43771 perinates were monitored in 29 hospitals of Anhui from Oct. 1986 to Sep. 1987. Among them were 467 perinates with birth defects (10.67‰)and 1600 perinates death ( 36.55‰). And there was no difference in sex in the two groups (P>0.05).The major birth defects were hydrocephaly, anencephaly and cleft lip with cleft Palate in descending order of frequency. The incidence rate of neural tube defect ranked the first in the north of Anhui and extremitas malformation occurred commonly in the other parts. The incidence of birth defects, was higher in rural areas ( 16.35‰) than in cities ( 7.37‰) . The difference was significent statistically ( P>0.05 ) . The causative factors seem to be associated with consanquinesus parants, low cultural level, pregnancy≤20 and≥35 years, multiple gravide, muliple pregnancy and twin pregnancy etc.

关 键 词：围产儿 出生缺陷 畸形 流行病学 

分 类 号：R726.201[医药卫生—儿科]