三种饲料添加剂对肉鸡小肠肥大细胞数量分布的影响  

Effect of Three Feed Additives on Number of Mast Cells in Small Intestine of Broiler

作　　者：李芙燕[1] 陈耀星[1] 王子旭[1] 王青丽[1] 呙于明[2] 张龙超 

机构地区：[1]中国农业大学动物医学院,北京100094 [2]中国农业大学动物科技学院,北京100094

出　　处：《动物医学进展》2006年第2期65-68,共4页Progress In Veterinary Medicine

基　　金：国家自然科学基金(30270960;30471247)

摘　　要：将20只1日龄健康AA肉鸡随机分为4个处理组：对照组（基础日粮），硫酸抗敌素组（基础日粮＋硫酸抗敌素100mg／kg），幼康宝组（基础日粮＋幼康宝500mg／kg）和丁酸钠组（基础日粮＋丁酸钠500mg／kg）。试验7周后，采用组织学技术，研究了肉鸡小肠肥大细胞的形态及数量分布。结果显示，①比较各试验组和对照组，小肠肥大细胞的形态没有明显的变化，多存在于肠腺周围和肠绒毛固有层。②各试验组的小肠肥大细胞数量均高于对照组（0．1％-30％），而且在备试验组中又以丁酸钠组的肥大细胞数最多，硫酸抗敌素组次之，幼康宝组最少。③各试验组和对照组小肠肥大细胞数均从前向后逐渐减少，十二指肠的肥大细胞最多，空肠的次之，回肠的较少。3种添加剂均可不同程度地促进肉鸡小肠肥大细胞的增殖，提高小肠黏膜免疫水平，并且丁酸钠的效果明显优于硫酸抗敌素和幼康宝。Twenty healthy one-day-old AA broilers .were divided into 4 groups in this study： Control group with basic diet, colistin group with basic diet and 100 mg/kg of colistin, Youkangbao group with basic diet and 500 mg/kg Youkangbao, and sodium butyrate group with basic diet and 500 mg/kg of sodium butyrate. After seven weeks, the distribution and structure of mast cell were observed in the small intestine of AA broilers by light microscope. Results were as follows：①There were not significant differences in the morphological change of mast cells in small intestine among control group and treatment groups. These cells were often found in the around of intestinal gland and the lamina propria of intestinal villus. ②The number of mast cells in experimental groups was more than that in control group, especially in both sodium hutyrate group and colistin group.③The number of mast cells in the small intestine decreased by degrees from cranial to caudal in all groups. This study indicated that three feed additives could be used to increase mast cell number, improving the mucosal immunity of small intestine in broiler, especially in the group of sodium hutyrate.

关 键 词：饲料添加剂 肥大细胞 黏膜免疫 小肠 肉鸡 

分 类 号：S816.7[农业科学—饲料科学]