促红细胞生成素在多发伤病人中的应用  

Application of rhEPO in patients with multiple injuries

作　　者：汪智卿[1] 肖接承[1] 凌伟华[1] 胡玉道[1] 

机构地区：[1]苏州大学医学院附属第一人民医院急诊外科,苏州215006

出　　处：《中国现代医药杂志》2005年第6期14-17,共4页Modern Medicine Journal of China

摘　　要：目的评价促红细胞生成素在多发伤患者中应用的临床意义及安全性。方法85例多发伤患者随机分成2组,给药组(45例)于入院后即予重组人促红细胞生成素(rhEPO)1万U/D皮下给药,连续用药10天;对照组(40例)不给予rhEPO,其它处理同给药组。将两组的治疗结果进行分析。结果两组患者Hb恢复及HCT有显著差异,而收缩压、舒张压及血小板计数差异无统计意义。结论早期应用rhEPO进行人红细胞动员,可改善患者贫血及生活质量,促进恢复。使用中未发现明显不良反应。Objective To evaluate the clinical significance and safety of rhEPO in the application of treating patients with multiple injuries. Methods Eighty-five patients with multiple injuries were randomly divided into two groups. The experimental group （45 cases） received rhEPO for ten days while the control group （40 cases） did not receive rhEPO. The results of blood tests in the two groups were analyzed. Results There were significant difference between the two groups in Hb and HCT,and no significance differences in blood pressure and blood platelet. Conclusion Erythrocyte mobilization by early applicantion of rhEPO could effectively relieve degree of anaemia and improve the quality of life. No apparent harmful reaction were found in the course of treatment.

关 键 词：多发伤 重组人促红细胞生成素 

分 类 号：R641[医药卫生—外科学]