青木香(Aristolochia debillis Sieb.et Zucc.)的消炎和镇痛活性(英文)  

Anti-inflammatory and Analgesic Activites of Aristolochia Debillis Sieb.et Zucc. Aqueous Extract

作　　者：吕金海[1] 舒孝顺[2] 伍贤进[1] 

机构地区：[1]怀化学院生物工程系,湖南怀化418008 [2]长沙理工大学生物系,湖南长沙410006

出　　处：《山西中医学院学报》2006年第1期18-20,共3页Journal of Shanxi College of Traditional Chinese Medicine

基　　金：湖南省教育厅资助课题, No:04A042~~

摘　　要：目的:检测青木香(AristolochiadebillisSieb.etZucc.)的块根水提取液的消炎和镇痛效果及毒性。方法:用蛋清诱导法、热板法和扭体法。结果:青木香的块根水提取液无毒性,1000mg/kg,i.g.的青木香块根水提取液比生理盐水的消炎和镇痛效果明显,比200mg/kg,i.g.乙酰水杨酸的消炎效果好,2000mg/kg,i.g.的青木香块根水提取液比乙酰水杨酸的消炎效果更加显著。结论:青木香具有较好消炎和镇痛活性,无毒性。Objective：To determine anti-inflammatory, analgesic and acute toxicity effects of A ristolochia debillis Sieb. et Zucc. aqueous extract. Methods：Egg：-albumin-induced edema in rats, hot-plate and acetic acid-induced abdominal constriction tests models respectively in mice were used. Results： The aqueous extract （ 1 000 mg/kg, i.g. ）had significant analgesic and anti-inflammatory effects compared to physiological saline solution, and more significant anti-inflammatory effects compared to acetylsalicylic acid （ 200 mg/kg, i.g. ）. 2 000 mg/kg extract（i.g.）had a very signif- icant anti-infltunmatory effects compared to acetylsalicylic acid （ 200 mg/kg, i.g. ）. Conclusion： The aqueous extract had a significant analgesic and anti-inflammatory effects and had no acute toxicity.

关 键 词：青木香(Aristolochia debillis Sieb.et Zucc.) 提取液 消炎 镇痛 

分 类 号：R285.5[医药卫生—中药学]