硒铜对氯化镉致绵羊病理损伤的保护效应  

PROTECTIVE EFFECTS OF SELENIUM AND COPPER ON CADMIUM-INDUCED PATHOLOGICAL LESIONS IN SHEEP

作　　者：马卓[1] 刘宗平[1] 朱宣人[1] 

机构地区：[1]甘肃农业大学动物医学系,南京农业大学动物医学院

出　　处：《甘肃科学学报》1996年第2期16-20,共5页Journal of Gansu Sciences

基　　金：甘肃省自然科学基金

摘　　要：用口服和肌注的方法在１２只绵羊中进行了镉中毒与硒铜颉颃其毒性的实验研究。结果表明，镉中毒组绵羊在实验的２０天左右即出现明显的临床病理学变化，特征为典型的低色素正细胞性贫血。实验期满１００天后屠杀、剖检，并进行病理组织学和超微结构观察，发现在全身小动脉血管及肝、肾、心、肺等器官有严重的病理损伤。补硒和铜可以减轻上述变化，表明硒和铜可共同颉颃镉在绵羊的毒性。An experimental study on the cadmium poisoning and its detoxification by selenium and copper was carried out through oral administration and intramuscular injection in 12 sheep.On the20th day after treatment,some prominent clinicopathological changes,including typicalhypochromic normocytic anemis,began to appear in the Cd treated group.Histopathological and ultrastructural lesions occurred in the arteriole,liver,kidney,lung,heart and central nervous system etc.At the end of the study.In the supplemented group with selenium and copper,however,above-mentioned lesions were mild. It follows that selenium and copper can simultaneously antagonize thd toxicity f cadmium in sheep.

关 键 词：硒 铜 中毒 绵羊 氯化镉 环境污染 

分 类 号：X503.221[环境科学与工程—环境工程]