丙泊酚复合小剂量氯胺酮用于无痛人流的效果观察  

Treatment Efficacy of Propofol Combined with Small Dose Ketamine in Indolence Misbirth

作　　者：黄丽霞[1] 纪浩聪[1] 高晓枫[1] 

机构地区：[1]惠州市中心人民医院麻醉科,广东惠州516001

出　　处：《河南职工医学院学报》2006年第1期20-21,共2页Journal of Henan Medical College For Staff and Workers

摘　　要：目的比较单纯应用丙泊酚与丙泊酚复合小剂量氯胺酮应用于人工流产手术的麻醉效果。方法80例自愿终止妊娠的孕妇,随机分为P(丙泊酚组),K(丙泊酚复合氯胺酮组)两组,麻醉后观察两组病人的丙泊酚用量、入睡时间、苏醒时间、离院时间、麻醉效果及术后不良反应。结果两组病人年龄、体重、手术时间相比较无显著差异。K组丙泊酚用量(1.8±0.2mg.kg-1)明显少于P组(2.5±0.1 mg.kg-1)入睡时间两者相比较无明显差异,苏醒时间K组较P组略长,但相差时间平均1 min左右。离院时间K组也较P组略长平均相差2 min。镇痛效果观察:K组均优于P组,组间比较有显著差异。术后不良反应情况:K组术后1例出现轻微恶心呕吐,无其他不良反应。P组术后无恶心呕吐发生,但有3例下腹疼痛。结论丙泊酚复合小剂量氯胺酮用于无痛人流的麻醉效果较单纯使用丙泊酚优越。Objective To compare the anesthetic effect of single dose ketamine applied in indolence misbirth. Methods Eighypregnah propofol with propofol compound small t women who volunteered to stop gestation were randomly divided into P （ propofol ）, K （ propofol compound ketamine ） groups. After housing, the propofol dosage reaction of two operative time. fall asleep time, revival time, leave hospital time, anesthetic effect and postoperative badness group patients were observed. Results There was no prominent difference age, avoirdupois and of K group（1.8 ± 0.2 mg/kg） was less than P group（2.5 ± 0.1 mg/kg）. The sleepingtime of K group was about one minute longer than P group on average. Leaving hospitaltime of K group was longer than P group, about 2 minutes. Anesthetic effect was observed ： the effect of K group was more excellent than P group. Postoperative reaction ： there was no reaction but one who had mild vomit in K group. Nobody had vomit except three patients had abdomen ache in P group. Conclusion The anesthetic effect of propofol compound small dose ketamine applied in indolence misbirth is more superiority than single propofol.

关 键 词：丙泊酚 小剂量氯胺酮 无痛人流 

分 类 号：R713.4[医药卫生—妇产科学]