肠道黏膜免疫  

Intestinal Mucosal Immunity

作　　者：范骏[1] 谢勇（审校者）[2] 

机构地区：[1]南昌大学第一附属医院消化研究所（博士研究生）,330006 [2]南昌大学第一附属医院消化研究所

出　　处：《国际免疫学杂志》2006年第2期111-115,共5页International Journal of Immunology

摘　　要：肠道免疫系统由大量弥散分布在肠黏膜上皮内和固有层的免疫细胞和免疫分子、以及诸如peyer’spatches(PP)等肠相关性淋巴组织等组成。小肠PP结为肠黏膜免疫主要诱导部位,肠黏膜上皮和固有层为主要效应部位。B细胞、T细胞在PP结诱导后,分化、成熟,并移行到黏膜效应部位,发挥免疫效应功能。The intestinal immune system consists of many immune cells and molecules scattered throughout the lamina propria and epithelium of the mucosa, as well as organised lymphatic tissues such as the peyer＇s patches. The peyer＇s patches which placed in the small intestine are the primary inductive sites. The main effector site is the lamina propria and epithelium of the mucosa, where mature T and B ceils migrate following induction in the peyer＇ s patches. Effector mechanisms that protect mucosal surfaces include CD8^＋ T cells and CD4^＋ T cells for cytokine production and IgA response.

关 键 词：肠相关淋巴组织 免疫细胞 免疫分子 

分 类 号：R392[医药卫生—免疫学]