兔出血症病毒分子生物学研究进展  

Advance in Molecular Biology of Rabbit hemorrhagic disease virus

作　　者：张玉颖[1] 刘光清[2] 吴润[1] 

机构地区：[1]甘肃农业大学动物医学院,甘肃兰州730070 [2]浙江省农业科学院农业部病毒学与生物技术重点实验室,浙江杭州310021

出　　处：《动物医学进展》2006年第3期9-13,共5页Progress In Veterinary Medicine

基　　金：浙江省自然科学基金资助项目(Y305047)

摘　　要：兔出血症是由兔出血症病毒引起的一种急性、高度致死性传染病,病死率可高达100%,给养兔业带来了巨大的经济损失。近年来,随着对其研究的不断深入,在病毒分子生物学方面取得了很大的进展。文章主要从基因组结构及功能、编码的结构蛋白与非结构蛋白、基因疫苗等方面系统阐述了兔出血症病毒分子生物学方面的研究进展,同时,提出了存在的问题和展望。为进一步研制兔出血症病毒基因工程疫苗及诊断试剂提供理论基础,以期能更有效地防治此病。Rabbit hemorrhagic disease is a kind of acute, lethal infectious disease caused by Rabbit hemorrhagic disease virus（RHDV）. It can cause death of rabbits in 100% and be responsible for large economic losses to rabbit producers. The great progress was made in molecular biology of Rabbit hemorrhagic disease virus after studying thoroughly these years. This article reviewed the advances in molecular biology of gehome, its coding proteins and non-coding proteins,gene vaccine and diagnostic technology of RHDV. Fu- ture developments and recent problems were mentioned. It will supply important theoretic foundation for researching immunity and diagnostic products of genetic engineering and detecting and preventing RHDV, in order to more effectively control the disease.

关 键 词：兔出血症病毒 分子生物学 

分 类 号：S852.659.6[农业科学—基础兽医学] S858.291[农业科学—兽医学]