清开颗粒对亚临床肝性脑病患者智力测试与诱发电位的影响  

Effect of Qingkai Granule on patients with subclinical hepatic encephalopathy of intelligence test and evoked potential

作　　者：刘龙民[1] 王灵台[2] 陈建杰[2] 高月求[2] 虞胜[3] 

机构地区：[1]上海中医药大学附属普陀医院,上海200062 [2]上海中医药大学附属曙光医院,上海200021 [3]上海市中医医院,上海200071

出　　处：《中成药》2006年第3期372-375,共4页Chinese Traditional Patent Medicine

摘　　要：目的:探讨亚临床肝性脑病中医治疗。方法:收集SHE患者60例,随机分为二组,中药清开颗粒组(30例)和乳果糖组(30例),用药二周,评价其对数字连接试验(NCT)、数字符号试验(DST)、诱发电位(EPs)的影响。结果:与对照组乳果糖比较,中药清开颗粒组可明显缩短NCT的时间,对DST亦有明显改善作用;AEPs、SEP的PL和IPL均有不同程度缩短,组间比较差异有显著性。结论:中药清开颗粒对SHE有较好的治疗作用,发挥中医药优势,在SHE的防治方面取得进展。AIM ： To explore the treatment of subclinical hepatic encephalopathy （SHE） by traditional Chinese medicine. METHODS： Sixty patients with SHE were randomized into two groups： treatment group with 30 cases treated by Qingkai Granule and control group with another 30 cases treated by lactulose. They were all treated for two weeks. The evoked potentials （Eps） were measured, moreover, number connection test （NCT） and digit symbol test （DST） were conducted. RESULTS： In treatment group, the period for NCT was shorter and the DST also improved apparently; peak latency （PL） and interpeak latency （IPL） of SEP and AEPs were shorter to different degrees, with significant differences among groups. CONCLUSION： Qingkai Granule acts to effectively increase the learning, memory and space cognitive capacities in patients, and improves the nerve electrophysiology in patients.

关 键 词：亚临床肝性脑病 清开颗粒 智力测试 诱发电位 中医治疗 

分 类 号：R287[医药卫生—中药学]