胫骨定量超声速率在检测代谢性骨病中的诊断价值  

Diagnostic value of quantitative tibial ultrasound velocity test in different metabolic bone diseases

作　　者：刘怀成[1] 邢小平[1] 夏维波[1] 王鸥[1] 胡莹莹[1] 

机构地区：[1]中国协和医科大学中国医学科学院北京协和医院内分泌科,北京100730

出　　处：《中国骨质疏松杂志》2006年第1期22-24,共3页Chinese Journal of Osteoporosis

摘　　要：目的评估胫骨骨超声速率(SOS)在检测代谢性骨病中的诊断价值。方法用Sound Scan2000型胫骨骨超声测定仪(以色列Myriad公司制造)测定代谢性骨病患者和对应的正常人的胫骨骨超声速率。结果①原发性甲状旁腺机能亢进(甲旁亢)、低P抗D软骨病、肾小管酸中毒、库兴氏综合征以及甲亢患者均较相应的正常值明显下降(P<0·01);②原发性骨质疏松患者、甲旁亢患者治疗后的胫骨骨超声速率较治疗前有显著性升高(P<0·05,P<0·01);③甲旁亢患者的胫骨骨超声速率与双能X线测定的骨密度有很好的相关性。结论胫骨超声速率(SOS)能够提供代谢性骨病的信息及骨强度的改变,对诊断代谢性骨病、骨质疏松症以及治疗前后骨密度的改变有一定的临床意义。Objective To evaluate the quantitative tibia ultrasound velocity test in different metabolic bone diseases. Methods Totally, 192 cases of different metabolic bone diseases and 518 normal subjects were included in this study. Speed of sound（SOS） were mearsured in the middle of tibia by ultrasound scan [ Sound Scan 2000 Myriad Isereal ]. Results （1）There was no significant difference in the tibia SOS value between hypophosphatemia and the normal subjects （P 〉 0.05 ）; the tibia SOS value of hyperthyroidism, hyperparathyroidism, hypophosphatemic vitamin D-resistant Ricket, Cushing＇s syndrome, hypophosphatemia and renal tubular acidosis were obviously lower than that of normal reference value（ P 〈 0.01 ） ; （2）The tibia SOS value of primary osteoporosis and hyperparathyriodism were increased compared with that before the treatment; （3）The tibia SOS was significant positive correlated with DEXA of hyperthyroidism. Conclusion The tibia values of SOS provides a meaningful diagnostic criteria of bone density and bone quality.

关 键 词：胫骨超声速率 代谢性骨病 

分 类 号：R681[医药卫生—骨科学] R735.7[医药卫生—外科学]