水解牡蛎钙在大鼠体内的代谢和利用  

MetabolismandUtilizationofCalciumDerivedfromHydrolysedOysterShelinRats

作　　者：沈新南[1,2] 陆瑞芳[1,2] 吴岷[1,2] 葛福平[1,2] 陆日生 

机构地区：[1]上海医科大学公共卫生学院营养与食品卫生学教研室 [2]空军上海第一医院同位素室

出　　处：《中华预防医学杂志》1996年第2期91-93,共3页Chinese Journal of Preventive Medicine

摘　　要：为了解水解牡蛎钙的生物利用率，作者以含钙量相等（４５ｍｇ／ｄ）的水解牡蛎钙、碳酸钙、氯化钙喂饲缺钙动物模型大鼠４周，采用原子吸收法和ＥＤＴＡ络合滴定法测定了大鼠的血钙、尿钙、粪钙和骨钙，骨密度仪测定骨密度。结果表明，水解牡蛎钙组大鼠的钙吸收率和存留率分别为６７．３％±１６．７％和６４．６％±１７．５％，股骨骨钙含量为１３１．２±１．４８ｍｇ／ｇ，股骨骨密度（ＢＭＣ／ＢＷ）为０．３１８±０．０３４ｇ／ｃｍ２，均显著高于碳酸钙对照组。三组大鼠的血钙含量、体重增重和摄食量差异无显著性。提示水解牡蛎钙比常用钙剂碳酸钙更有利于机体的吸收和利用。Experimentalratsmodeledoncalciumdeficiencywerefedwithcalciumderivedfromhydrolysedoystershel,calciumcarbonateandcalciumchloriderespectively,equivalentto45mgaday,forfourweekstostudytheirbioavailability.Calciumcontentsintheblood,urine,fecesandboneofratsweredeterminedwithatomicabsorptionspectrometryandEDTAcomplextitration,andtheirbonedensitywasmeasuredwithdensitometry.Resultsshowedproportionsofcalciumabsorp-tionandretentionwere67.3%±16.7%and64.6%±17.5%,respectively,inratsfedwithcalciumfromhydrolysedoyster,andtheirfemurcalciumcontentandbonedensity(BMC/BW)131.2±1.48mg/gand0.318±0.034g/cm2,respectively,significantlyhigherthanthoseintheratsfedwithcal-ciumcarbonate.Therewerenosignificantdiferenceinbloodcalciumcontents,weightgainsandfeedintakebetweenthosethreegroupsofrats.Itsuggeststhatcalciumderivedfromhydrolysedoystershelmaybeabsorbedandutilizedmoreeasilythancalciumcarbonate.

关 键 词：钙 生物利用率 水解牡蛎 

分 类 号：Q582[生物学—生物化学]