草本水杨梅中芳香类化合物的分离与鉴定  

Isolation and structure identification of phenolic compounds from Geum aleppicum Jacq.

作　　者：李刚[1] 杨晓虹[1] 王艳[1] 牟凤辉[1] 董雷[1] 陈滴[1] 李怀林[1] 

机构地区：[1]吉林大学药学院药物化学教研室,吉林长春130021

出　　处：《吉林大学学报（医学版）》2006年第2期196-198,共3页Journal of Jilin University：Medicine Edition

基　　金：国家留学基金委资助课题(19995003)

摘　　要：目的:分离和鉴定草本水杨梅中芳香类化合物。方法:采用薄层色谱分析、硅胶柱色谱法纯化,经理化常数、光谱学方法分离鉴定6个化合物的结构。结果:从草本水杨梅全草中共分离得到6个芳香类化合物,分别确定其结构为苯甲酸(Ⅰ)、没食子酸(Ⅱ)、水杨酸(Ⅲ)、香草醛(Ⅳ)、3,4,5-三羟基苯甲醛(Ⅴ)、3,4,5-三羟基苯甲酸乙酯(Ⅵ)。结论:化合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ均为首次从草本水杨梅中分得的芳香类化合物。Objective To isolate and identify the structures of the phenolic compounds from Geum aleppicum Jacq.. Methods The structures of six compouds were determined by the physical and chemical data and spectroscopic analysis after the purification by thin-layer chromotography and silical gel column chromatography. Results Six phenolic compounds were isolated from Geum aleppicum Jacq. , and their structures were established to be benzoic acid （ Ⅰ ）, gallate acid （ Ⅱ ）, salicylic acid （ Ⅲ ）, vanilin （Ⅳ ）, 3, 4, 5-trihydoxybenzoic dehyde （ Ⅴ ） and 3, 4, 5-trihydoxybenzoic acid, ethyl ester （Ⅵ）. Conclusion The compounds Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ are isolated from this plant for the first time.

关 键 词：草本水杨梅 分离鉴定 芳香化合物 

分 类 号：O656[理学—分析化学]