高尿酸血症与冠心病的相关性研究  

STUDY OF CORRELATION BETWEEN HYPERURICEMIA AND CORONARY HEART DISEASE

作　　者：程纯[1] 吴士尧[1] 殷兆芳[1] 许左隽[1] 徐济民[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院心内科,200011

出　　处：《老年医学与保健》2006年第1期34-35,45,共3页Geriatrics & Health Care

摘　　要：目的探讨高尿酸血症与冠心病的相关性。方法选择冠心病患者180例,分为急性冠脉综合征组及稳定型心绞痛组,另设对照组150例。分别测定血清尿酸、血糖以及血压、体重指数(BMI)、血脂水平。结果冠心病患者尤其是急性冠脉综合征患者血清尿酸水平与对照组相比,有统计学显著意义(P<0.01),相关分析提示血清尿酸水平与冠心病显著相关。结论高尿酸血症是冠心病尤其是急性冠脉综合征的危险因素之一。Objective To determine the relationship between hyperuricemia and coronary artery disease（CAD）. Methods Serum concentration of uric acid was measured and other biochemical assessments such as serum level of Glucose, TG,TC,LDL-c, HDC-c were determined at a fasting state in 180 patients who have undergone coronary angiography. Results Serum level of uric acid in CAD group was significantly higher than that in normal coronary artery group. Correlation analysis results showed that serum uric acid level was positively and significantly related to CAD age.Glucose, TG, LDL-c and body mass index （P 〈 0.05 or P 〈 0.01 ,respectively）. Serum uric acid level hears an intimate relationship with the occurrence of CHD.

关 键 词：高尿酸血症 冠状动脉疾病 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]