羊FSHR基因5′端转录启动调控区的生物学特性  

Biological Characteristics of the 5′ Regulatory Region of FSHR Gene in Sheep

作　　者：柳淑芳[1] 杜立新[2] 王爱华[2] 

机构地区：[1]中国水产科学研究院黄海水产研究所,青岛266071 [2]中国农业科学院畜牧研究所,北京100094

出　　处：《遗传》2006年第4期427-431,共5页Hereditas（Beijing)

基　　金：国家自然科学基金资助项目(编号:30270949)~~

摘　　要：文章对小尾寒羊、滩羊和澳洲绵羊等繁殖性状不同的3种绵羊与排卵有关的FSHR基因5′端转录启动调控区进行了克隆和分析,通过对FSHR基因的15个转录调控元件序列进行比较,结果表明,羊不同品种FSHR基因的转录调控元件序列之间没有差异。这说明绵羊的品种与FSHR基因5′端转录启动调控区的相关性不强,排除了因转录调控元件突变而影响转录调节能力的可能性。The 5＇ transcriptional promoter regulation region of FSHR gene was cloned and analyzed in Little-tailed Han sheep, Tan sheep and Australian Merino sheep. Comparison of 15 transcriptional regulatory elements in the FSHR gene showed no difference in the regulatory region of FSHR gene among the three breeds. The results showed no association between sheep breeds and 5＇ transcriptional promoter regulation region and eliminated the possibility that the mutation of transcriptional regulation region can affect the transcription of FSHR gene in sheep.

关 键 词：FSHR基因 转录启动调控区 羊 

分 类 号：S826[农业科学—畜牧学]