铜绿假单胞菌在老年患者中的分布及耐药性分析  

Analysis of pseudomona aeruginosa distribution in senile patients and its drug resistance

作　　者：姚明兰[1] 张瑞琴[2] 张润梅[2] 徐辉[2] 康建邦[2] 

机构地区：[1]山西医科大学第二医院干部保健科,太原030001 [2]山西医科大学第二医院药剂科,太原030001

出　　处：《中国药物与临床》2006年第3期200-202,共3页Chinese Remedies & Clinics

基　　金：山西省科技攻关基金资助项目(051095-5)

摘　　要：目的了解2004年1月至2005年6月铜绿假单胞菌在我院老年患者中的分布特点及药敏特征,为临床合理应用抗菌药物提供科学依据。方法对老年患者的各种临床标本进行细菌的分离培养,再通过ATBExpression微生物鉴定系统鉴定,采用K-B纸片进行药敏测定结果。结果共检出255株铜绿假单胞菌,主要分布在呼吸科、干部病房;铜绿假单胞菌在痰标本中的阳性率最高92.5%;铜绿假单胞菌对头孢唑啉(CAZ)、亚胺培南(IPM)、环丙沙星(CIP)耐药率<30%,其余药物都>35%。讨论对老年患者进行病原菌跟踪监测及药敏实验,对控制老年患者的感染及临床医师合理使用抗生素是不可缺少的重要环节。Objective To investigate the pseudomonas aeruginosa＇s characteristic and drug sensitivity in elder patients in our hospital from Jan,2004 to Jun,2005,and provide scientific basis for rational employment of antibiotics in clinic.Methods The clinical specimens collected from elder patients were cultured to isolated bacteria,then identificated by ATB Expression microb identification system. The drug sensitivity test was performed using Kirbybauer disk diffusion method.Results Two hundred and fifty-five strains of pseudomonas aeruginosa were detected and they distributed mainly in departments of respiratory and cadre ward. The positive rate of pseudomonas aeruginosa in sputum specimen was the highest 92.5%. The resistance rate of pseudomonas aeraginosa to CAZ,IPM and CIP was less than to 30%,to other drugs was greater to 35%.Conclusion It is necessary and important to follow up and monitor pathogenic bacteria and do drug sensitivity test in elder patients, which played very important role in controlling elder patient infection and giving the instruction on rational antibiotic using for clinical doctors.

关 键 词：老年人 抗药性 细菌 革兰氏阴性菌感染 

分 类 号：R446.5[医药卫生—诊断学]