呋喃唑酮与土霉素合用对幽门螺杆菌体外抗菌作用的研究  

STUDY ON ANTI-HELICOBACTER PYLORIDIS'S ACTIVITY BY CO-ADMINISTRATION OF FURAZOLIDINE AND TERRAMYCINE IN YITRO

作　　者：焦文才[1] 邱丽萍[1] 朱坤杰[1] 李清漪[1] 王茹玲[2] 李富华[2] 张玲[2] 李秀臣 

机构地区：[1]齐齐哈尔医学院药理学教研室 [2]齐齐哈尔医学院第一附属医院药剂科 [3]拜泉县卫生学校

出　　处：《齐齐哈尔医学院学报》1996年第2期87-89,共3页Journal of Qiqihar Medical University

摘　　要：采用Skirrow琼脂培养基分离、培养、鉴定出幽门螺杆菌。用固体之平皿打孔法测定呋喃唑酮、土霉素碱及两药合用的抗菌活性。用Skirrow琼脂培养基稀释法,测定其MIC和MIC90量(mg/L)。结果表明,呋喃唑酮与土霉素碱合用对幽门螺杆菌的抑制有很强的协同作用。Helic obacter Pyloridis ( HP ) was cultured in Skirrow agar culture medi_ m then isolated and indentified. The antibacterial actirity of f urazolidine (FZ)and Tcrramycine (TY) aad combination of them were determined by Skirrow- agar medium dilution assay. The results showed that the antibac-erial activity of combination of FZ and TY was more potent then that of either of them alone.

关 键 词：呋喃唑酮 土霉素 幽门螺杆菌 抗菌活性 药理学 

分 类 号：R969.2[医药卫生—药理学] R378.99[医药卫生—药学]