B超下主动脉壁厚度与血清载脂蛋白的关系  

Relationship between Aorta Wall Thickness in B-Mode Echocardiography and Serumal Apoproteins

作　　者：李自成[1] 白春梅[1] 曹茂银[1] 胡剑峰[1] 付承主 

机构地区：[1]湖北医科大学附二医院心内科

出　　处：《中国医学影像技术》1996年第4期300-302,共3页Chinese Journal of Medical Imaging Technology

摘　　要：Ｂ型超声心动图下测量了１２８例高血压病患者主动脉壁厚度（ＡＷＴ），同时检测了血脂指标。结果显示：与正常血脂组比较，高脂血症组血清载脂蛋白Ｂ（ＡｐｏＢ）水平和ＡＷＴ均增加（Ｐ＜均０．０１），ＡｐｏＡ１和ＡｐｏＡ１／ＡｐｏＢ均降低（分别Ｐ＜０．０５和Ｐ＜０．０１），合并冠心病的患病率亦增高（Ｐ＜０．０５）。直线相关分析显示：ＡＷＴ与ＡｐｏＢ呈正相关（ｒ＝０．３１４），与ＡｐｏＡ１（ｒ＝－０．４１１）和ＡｐｏＡ１／ＡｐｏＢ（ｒ＝－０．７５１）呈负相关，Ｐ＜均０．０１。经逐步回归，筛选对ＡＷＴ有显著作用的血脂指标是ＡｐｏＡ１／ＡｐｏＢ。The aorta wall thickness (AWT) was measured wiht B-mode echocardiography in 128 patients with primary hypertension. The blood lipids level were simutaneously determined. The results showed that compared with normal lipidemia group, serumal ApoB and AWT were increased (all P<0. 01),ApoA1 and the ratio of ApoA1/ApoB were decreased (P<0.05&P<0.01 respectively), and the prevalence rate of coronary heart disease was elevated P<0.05), in hyperlipidemia group. The correlation analysis suggested the AWT has a linear positive correlation with ApoB (r=0.314), and negative correlation with ApoA1 (r=-0. 411) and ApoA1/ApoB (r=-0.751) (all P<0.01). The stepwise regression analysis showed that blood lipid parmeters which play a significant role in AWT were sifted out and result is ApoA1/ApoB.

关 键 词：超声心动图 主动脉壁厚度 载脂蛋白 高血压 

分 类 号：R540.45[医药卫生—心血管疾病] R544.104[医药卫生—内科学]