应用放射性微球技术检测激素性肌组织血流量的实验研究  

Quantitative Measurement of Hormonal Muscular Blood Flow in Rabbits by Radioactive Microsphere

作　　者：邹锦慧[1] 李景田[2] 吉燕翔[3] 张慧明[1] 周小璜[2] 李伯灵[2] 林拓[3] 

机构地区：[1]韶关学院医学院解剖教研室,广东韶关512026 [2]韶关学院医学院药学教研室,广东韶关512026 [3]广东省粤北人民医院核医学科,广东韶关512026

出　　处：《四川解剖学杂志》2006年第1期16-18,共3页Sichuan Journal of Anatomy

基　　金：韶关市科技计划项目[韶科(卫)2004-28]

摘　　要：目的应用放射性微球技术检测激素性兔肌组织血流量。方法20只成年兔分为2组,1组为对照组,另1组给予地塞米松注射8周,采用放射性微球技术测量兔肌组织血流量。结果对照组肌组织中,以膈的血流量最高(P<0.01),上肢肌血流量高于下肢肌(P<0.05);激素组肌组织血流量较对照组低(P<0.01),降低幅度最明显的为膈。结论长程使用糖皮质激素可降低兔肌组织血流量。Objective To quantitatively measure hormonal muscular blood flow in rabbits by radioactive microsphere techniques. Metheds 20 rabbits were divided into 2 groups randomly, 10 were used as a control group, 10 were injected the dexamethasone in 8 weeks as modal group. The muscular blood flow in 2 group Rabbits were measured with radioactive microsphere techniques. Results In the control group, the blood flow of diaphragm was the highest among all muscular tissue（ P 〈0.01）. The blood flow of upper limb muscles was significantly higher than that of lower limb muscles（ P 〈0.05）. The muscular blood flow of modal group was significantly less than that of control group（ P 〈0.01）. The blood flow of diaphragm was significantly lower in modal group than other muscles. Conclusion Long-term glucocorticoid treatment reduced the muscular blood flow in rabbits.

关 键 词：放射性微球技术 糖皮质激素 肌 血流量 

分 类 号：R817[医药卫生—影像医学与核医学]