S形动脉中的血流动力学研究  

Hemodynamics study on S-shaped arteries

作　　者：乔爱科[1] 刘有军[2] 张松[2] 

机构地区：[1]北京工业大学机电学院,北京100022 [2]北京工业大学生命科学与生物工程学院,北京100022

出　　处：《医用生物力学》2006年第1期54-61,共8页Journal of Medical Biomechanics

基　　金：北京市教委项目资助(KM2004100050007)

摘　　要：目的探索动脉直径大小对S形动脉血流动力学的影响。方法利用数值模拟方法,对具有不同直径的大小两种S形动脉模型在相同的边界条件下的血流动力学时空分布进行了分析。结果在大S形动脉中的二次流比小S形动脉中的要复杂;在弯曲动脉的内弯区存在较强的涡流;弯曲动脉中的压力和壁面切应力变化很剧烈,特别是在大模型中。结论S形弯曲动脉中的血流呈现复杂回流、二次流、压力和壁面切应力剧烈变化等特性,这些都可能影响到动脉内皮的功能及内膜增生。在利用人造或自体血管修复旁路狭窄动脉的手术中,应尽量避免采用S形动脉模型。Objeclive To understand the effects of the arterial size on the hemodynamics of S-shaped arteries. Method Numerical simulation method was applied to analyze the temporal and spatial distributions of hemodynamic variables in bothlarge and small S-shaped arterial models with different arterial diameters under identical boundary conditions, respectively. Result The secondary flow in the large S-shaped artery is more complex than that in the small one; stronger eddy flow occurred in the inner bends of curved arteries; pressure and wall shear stresses changed violently in the curved arteries, especially in the larger model. Conclusion The hemodynamics of S-shaped arteries may affect the function of arterial endothelium, and result in the thickening of the intima. It may be favorable to avoid using the S-shaped artery in operations to correct or bypass arterial stenosis when utilizing prosthetic or autologous vessels.

关 键 词：弯曲动脉 脉动流 壁面切应力 生物流体力学 数值模拟 

分 类 号：Q66[生物学—生物物理学]