统计分析方法研究胆结石成因——因子分析和回归分析  

The Study on Gallstone Formation by the Method of Statistics--Factor and Regression Analysis

作　　者：张完白[1] 邵可声[1] 李赛君[1] 丁晓春 周孝思[3] 傅贤波[3] 

机构地区：[1]北京大学技术物理系 [2]北京大学化学系 [3]北京医科大学第三医院

出　　处：《北京大学学报（自然科学版）》1990年第4期397-405,共9页Acta Scientiarum Naturalium Universitatis Pekinensis

摘　　要：本文利用红外光谱法测得的表征胆固醇型及胆色素型结石的11个特征峰的相对强度及等离子发射光谱法测出的16种无机元素的含量为变量,进行统计分析。对胆结石的成因进行了初步探索。R型因子分析及双重筛选逐步回归分析的结果都表明两类结石有不同的形成原因及相关的无机元素。This report tries to study the formation of gallstones by factor and regression analysis. The amount of inorganic elements is found in 20 gallstone samples by Inductively Coupled Plasma (ICP). These analyses show that they all contain 16 inorganic elements, in which Ca, Na, S, Cu, and P are main. Eleven of the characteristic peaks in these samples, which are 2933, 2902, 2867, 1465, 1377, 1056, 1665, 1571, 1251, 1697 in cm-1, are determined by IR.Six common factors account for 84.8% of the total variance contribution. Final factor loadings indicate that the first factor is related to S, Na and most of the characteristic peaks representing the comprehensive factor of gallstones. The second factor is correlated with Ba, Ca, Mg, Mn and P, which can be explained by the formation of phosphate in gallstones. The third factor is relevant to heavy metals such as Cn, Pb, Zn and S. Obviously, these three factors play important roles in the formation of gallstones.

关 键 词：胆结石 统计分析 因子分析 成因 

分 类 号：R657.420.2[医药卫生—外科学]