证候与方剂相关性的研究  

Study the Correlation between Syndromes and Formulas

作　　者：孙占全[1] 刘艳骄[2] 西广成[1] 黄晓华[2] 易建强[1] 黄璐琦[3] 

机构地区：[1]中国科学院自动化研究所复杂系统与智能科学实验室,北京100080 [2]中国中医科学院研究生院,北京100700 [3]中国中医科学院中药研究所,北京100700

出　　处：《中国中医基础医学杂志》2006年第2期150-152,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家973计划"证侯规范及其与疾病;方剂相关的基础研究"资助项目(2003CB517106);国家自然科学基金项目(90209034)

摘　　要：目的:运用信息熵的方法,对中国古代中风病的中医文献进行证候与方剂相关性的定量分析,确定证候与方剂之间的关联度。方法:熵可以度量任意形式变量的不确定性,基于熵的关联度法可以度量任意统计相关性,包括线性和非线性,将其用于解决证候与方剂的相关性问题。结果:通过关联度方法l、ogistic回归分析和相关系数三种方法的分析,可以看出某些中医证候与方药之间还是有一定的相关性。结论:通过对200例中风病人的古代医案的分析,结果表明用基于熵的关联度法来定量分析证、方之间的相关性是可行的。Objective： Study the correlation between syndromes and formulas quantificationally according to the ancient TCM literatures of stroke patients with the method based on information entropy and calculate their correlation rates. Methods： Entropy can measure arbitrary uncertainty of variables. Correlation rate based on entropy can measure arbitrary statistical dependences including linear and nonlinear correlation. The correlation rate method is used to analyze the correlation between syndromes and formulas. Results： Through the comparison between correlation rate method with logistic regression and correlation coefficient method, we can find that the result that there exist some correlation between some syndromes and formulas. Conclusion： Through the analysis of 200 ancient stroke patients＇ literature, the results illustrate that it is feasible to analyze the correlation between syndromes and formulas quantificationally with correlation rate method.

关 键 词：证候 方剂 关联度 熵 

分 类 号：R255.2[医药卫生—中医内科学]