The SARD variety of multi-fractality of ventricular epicardial mapping during ischemia  

作　　者：CHEN Ying Martyn P. Nash NING Xinbao WANG Yelin David J. Paterson WANG Jun 

机构地区：[1]State Key Laboratory of Modern Acoustics, Institute for Biomedical Electronical Engineering, Nanjing University, Nanjing 210093, China [2]Engineering Science and Bioengineering Institute, University of Auckland, Private Bag 92019, NZ [3]Laboratory of Physiology, University of Oxford, Parks Road, Oxford OX13PT, UK

出　　处：《Chinese Science Bulletin》2006年第7期809-814,共6页

基　　金：supported by the Wellcome Trust and British Heart Foundation;supported by the National Natural Science Foundation of China(Grant No.60501003).

摘　　要：We have analyzed cardiac ische- mia-reperfusion in an animal model using epicardial electropotential mapping. We investigated the rela- tionship between ischemia and variability of multi- fractality in epicardial electrograms. We present a new parameter called the singularity spectrum area reference dispersion (SARD) that clearly demon- strates the change in multifractility with the extent of myocardiaischemia. By contrasting the 3D ventricular epicardial SARD map with the activation map, we conclude that myocardial ischemia significantly in- fluences the variety of multifractality of ventricular epicardium electrograms and the SARD parameter is useful in correlating multifractality of epicardial elec- trograms with location of ischemia closely.We have analyzed cardiac ischemia-reperfusion in an animal model using epicardial electropotential mapping. We investigated the relationship between ischemia and variability of multi- fractality in epicardial electrograms. We present a new parameter called the singularity spectrum area reference dispersion （SARD） that clearly demonstrates the change in multifractility with the extent of myocardiaischemia. By contrasting the 3D ventricular epicardial SARD map with the activation map, we conclude that myocardial ischemia significantly influences the variety of multifractality of ventricular epicardium electrograms and the SARD parameter is useful in correlating multifractality of epicardial electrograms with location of ischemia closely.

关 键 词：局部缺血 SARD 非线性 基因定位 室性心外膜 

分 类 号：R54[医药卫生—心血管疾病]