电针对急性脑缺血家兔环核苷酸及血管紧张素Ⅱ的影响  

Effects or Electroacupuncture on contents of Cyclic Nucleotides and Angiotensin Ⅱ in Rabbits with Acute Cerebral Ischemia

作　　者：杨军[1] 李汉先[1] 吴有胜 许立天[1] 

机构地区：[1]湖北省武汉市第六医院,武汉职工医学院生理教研室

出　　处：《中国针灸》1996年第5期38-40,共3页Chinese Acupuncture & Moxibustion

摘　　要：２８只大耳白兔随机分成对照组（８只）、急性脑缺血组（８只）和针刺组（１２只）。夹闭家兔两侧颈总动脉使颅内血压急剧下降，造成急性脑缺血。分别测定正常、夹闭时和电针“人中”穴后家兔下丘脑及血浆中ｃＡＭＰ、ｃＧＭＰ和ＡⅡ含量。结果发现：急性脑缺血时，ｃＡＭＰ、ｃＧＭＰ浓度和ｃＡＭＰ／ｃＧＭＰ比值下降，脑中ＡⅡ浓度下降而血浆ＡⅡ水平升高。针刺“人中”后，可明显升高脑及血浆ｃＡＭＰ和ＡⅡ水平。Twenty-eight rabbits were randomly assigned to three groups,control group(8 cases),acute cerebral ischemia group (8 cases) and acupuncture group(12 cases).The common arotid artery of both sides were cliped,which caused sharp drop of intracranial pressure and led acute cerebral ischemia. Contents of cGMP,cAMP and angiotensin Ⅱ(All) in the hypothalamus and plasma were determined in normal,during clipping and after acupuncture of 'Renzhong'(GV26) point in rabbits.It was found that in acute cerebral ischemia, the contents of cAMP, cGMP and cAMP/cGMP ratio decreased,the brain content of All reduced and plasma level of All elevated.After acupuncture of Renzhong point, the levels of cAMP and All in the brain and plasma were increased significantly.

关 键 词：脑缺血 针灸疗法 电针 环核苷酸 血管紧张素Ⅱ 

分 类 号：R277.733[医药卫生—中医学] R246.6