分钟通气量对小儿呼气末异氟醚浓度的影响  

Effect ofminute volume on expired concentration of isoflurane in children

作　　者：杨经文[1] 谭玲[1] 孙丽丽[1] 刘进[1] 

机构地区：[1]四川大学华西医院麻醉科,成都市610041

出　　处：《临床麻醉学杂志》2006年第3期190-192,共3页Journal of Clinical Anesthesiology

摘　　要：目的探讨小儿麻醉中不同分钟通气量对小儿呼气末异氟醚浓度上升速度的影响。方法45例行四肢、下腹部及会阴手术的患儿随机分成三组,每组15例,潮气量设置分别为8 ml/kg(A组)1、0 ml/kg(B组)、12 ml/kg(C组),呼吸频率均设置为15次/分,挥发罐所开浓度为2%,持续观察PETCO2、吸入及呼气末异氟醚浓度(Fi,Fa)的变化,并以Fa/Fi作为平衡速度。结果三组的Fa/Fi差异有显著意义(P<0.05);三组的PETCO2分别为(44.33±1.09)、(38.67±1.29)和(34.80±0.78)mmHg,差异无显著意义(P>0.05)。结论小儿Fa随着分钟通气量的增加,平衡速度加快。Objective To investigate the effect ofminute volume on expired concentration of isoflurane in children. Methods Forty-five children undergoing abdominal surgery or limbs surgery were randomly allocated to 3 groups,with 15 children each. Ventilation was set at tidal volume of 8 ml/kg （group A）,10 ml/kg （group B） or 12 ml/kg （group C） respectively , with the same respiratory frequency of 15 breathes perminute and delivered concentration of 2% of isoflurane in all patients. Inspired and expired isoflurane concentration （Fi, Fa） and end tidal CO2 （PET CO2 ） were monitored after intubation. Results Fa/Fi of group A had a significant difference with that of group B and group C at every moment without any significant difference existed at 1,2,3,4 min, but with a significant difference existed at 5, 15,25,30 min. PET CO2 values of groupA, B and C were （ 44.33 ± 1.09）, （38.67±1.29） and （34.80 ± 0. 78） mmHg respectively. Conclusion minute volume has effect on Fa/Fi of isoflurane in children and Fa/Fi ratio rises faster with higherminute volume.

关 键 词：异氟醚 吸入麻醉 小儿 

分 类 号：R726.1[医药卫生—儿科]