精神病人伴骨折与正常骨折患者的骨矿物质含量对照研究  

The Study of the Changes of the Content of bone Mineral in Mental Patients with Fractures and Normal Fractures

作　　者：邱开封[1] 陈如冰[1] 邹翘璇[1] 肖勃[2] 宋建新[1] 施壮炎 

机构地区：[1]汕头大学医学院第一附属医院,广东汕头515041 [2]汕头大学精神卫生中心,广东汕头515041 [3]广东省汕头市珠池医院,广东汕头515041

出　　处：《河北医学》2006年第3期216-218,共3页Hebei Medicine

基　　金：2005年度汕头市重点科技计划项目(编号:汕府科[2005]116号)

摘　　要：目的:探讨精神病人伴骨折患者是否存在骨质疏松、血清无机盐指标和血清总碱性磷酸酶(ALP)等骨矿物质含量的异常。方法:采用病例对照对36例精神病人伴骨折患者与38例正常骨折病人进行研究,测定血清K+、Na+、Ca2+等无机盐、血清总碱性磷酸酶(ALP)和检测骨密度作为诊断骨质疏松的指标进行比较。结果:与正常对照组比较,患者组患骨质疏松的比例明显增高X2=4.252,P=0.039;患者组钠和钾含量与对照组无明显差异,ALP含量明显高于对照组(P<0.05),钙含量明显低于对照组(P<0.05)。结论:精神病人容易患骨质疏松和出现低钙,是骨折发生的高危人群。Objective： To explore the content of bone mineral in mental patients with fractures. Methods： Osteoporosis were diagnosed and the serum salts and alkaline phosphatase were determined in 36 cases of mental patients with fracture and 38 controls with fracture. Results： The results showed that there were significant difference in osteoporosis between mental patients group and controls group （ X^2 = 4. 252, P = 0. 039 ）, and no significant in Na ^＋, K ^＋ contents between mental patients group and controls group （ P 〈 0.05 ）, but ALP levels were higher in mental patients group than that in controls group （ P 〈 0.05 ）, and Ca^2 ＋ level were lower in mental patients group than that in controls group （P 〈 0.05 ）. Conclusion： The mental patients are easily suffered from osteoporosis and occurrence the low level of Ca^2＋ , they are high risk populations of fractures.

关 键 词：骨折 精神病人 骨质疏松 无机盐 碱性磷酸酶 

分 类 号：R683[医药卫生—骨科学]