肝硬化合并糖代谢异常患者中医证候研究  

The Study of Syndromes in Patients with Liver Cirrhosis Complicated by Abnormal Glucose Metabolism

作　　者：麦静愔[1] 徐列明[1] 成扬[1] 赵长青[1] 薛惠明[1] 叶细标[2] 

机构地区：[1]上海中医药大学肝病研究所 [2]复旦大学公共卫生学院,上海200032

出　　处：《上海中医药大学学报》2006年第1期29-32,共4页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海市重点学科建设基金资助项目(Y0302)

摘　　要：目的:前瞻性研究肝硬化合并糖代谢异常患者的证候特点及中医辨证分型。方法:运用问卷调查的方法,收集了73例肝硬化合并糖代谢异常患者的一般情况、临床证候特点及辨证分型资料,与34例2型糖尿病患者资料相比较,采用SPSS11.0统计软件进行组间差异分析及主成分分析。结果:肝硬化合并糖代谢异常组患者的证候特点与肝硬化组患者的证候特点较为相似,提示二者有相似的病理基础。根据临床诊断发现:肝硬化合并糖代谢异常组以肝郁脾虚证及肝肾阴虚证为主;肝硬化组以肝郁脾虚证及肝脾血瘀证为主;而糖尿病组则以阴虚证为主,其中包括肾阴亏虚及气阴两虚证。结论:肝硬化合并糖代谢异常患者以肝郁脾虚、瘀阻肝络为主证,2型糖尿病以阴虚为主证。Objective：To prospectively study the syndrome differentiation and symptoms of traditional Chinese medicine （TCM） in patients with liver cirrhosis complicated by abnormal glucose metabolism and type 2 diabetes mellitus.Methods： By inquiry the clinical characteristics of symptoms and signs, syndrome differentiation of TCM from 73 liver cirrhosis patients and 34 type 2 diabetes mellitus patients were collected The different significance analysis between groups and the principal component analysis were finished by SPSS 11.0 statistical software. Results： It was found that stagnation of liver-qi, deficiency of the spleen, and damp stasis were the three main syndromes, at the same time complicating by blood stasis,damp-heat,yin deficiency syndrome. Liver depression and spleen deficiency syndrome is the commonest syndrome in these patients, the second is deficiency of Yin of both liver and kidneys. Conclusions： Yin deficiency syndrome was the main syndrome in the type 2 diabetes mellitus patients, but the main syndrome of the liver cirrhosis complicated by abnormal glucose metabolism was liver depression and spleen deficiency, blood stasis of liver.

关 键 词：肝硬化合并糖代谢异常 证候 辨证分型 前瞻性研究 

分 类 号：R259[医药卫生—中西医结合]