莫家蝇抗菌肽提取及对鸡大肠杆菌病药效试验  

Extraction and Efficacy Colibacillosis in Vivo an in Vitro of Antibacterial Peptides of Musca Domestica

作　　者：屈军梅[1] 陈平洁[2] 李文平[1] 屈孝初[1] 唐保国 黄庭汝[2] 

机构地区：[1]湖南农业大学动物科技学院,长沙410128 [2]广东省农业科学院畜牧研究所,广州510640 [3]湖南华大饲料有限公司,长沙410128

出　　处：《中国畜牧兽医》2006年第3期56-58,共3页China Animal Husbandry & Veterinary Medicine

基　　金：广东省自然科学基金(032019)资助

摘　　要：体外抑菌试验结果证明抗菌肽对O1型血清大肠杆菌的药敏抑菌圈直径为19.3±0.32mm,以O1型大肠杆菌感染14日龄岭南黄肉用雏鸡,24 h后分别用抗菌肽高、中、低剂量及环丙沙星混饮给药,以比较其疗效。通过临床观察、尸体解剖、细菌检验结果表明,试验药物组与感染对照组差异极显著(P<0.01),即试验药物对鸡大肠杆菌病有良好疗效;抗菌肽高、中剂量与环丙沙星疗效相当(P>0.05),且不影响鸡只的正常增重(P>0.05)。The anti-germ efficacy of antibacterial peptides was compared with Ling-nanhuang in 14-day-old artificially infected chicken. Through clinical observation, carcass dissection and germ inspection, results showed that the difference between testing medicine group and the infections comparing group was dramatic, that is to say, the testing medicine had a good treating effect on colibacillosis; the treating effect of antibacterial peptides high dose group and mediate dose group were adjacent which of Lin-nanhuang to colibacillosis.

关 键 词：抗菌肽 大肠杆菌 疗效观察 

分 类 号：S852.69[农业科学—基础兽医学]