布洛芬溶液经皮释药量的二阶导数分光光度测定  

SECOND ORDER DERIVATIVE SPECTROPHOTOMETRY FOR TRANSDERMIC PERMEABILITY OF IBUPROFEN LIQUID

作　　者：张小玲[1] 邵青[1] 

机构地区：[1]浙江医科大学药学系

出　　处：《中国医药工业杂志》1996年第6期262-264,共3页Chinese Journal of Pharmaceuticals

摘　　要：用二阶导数分光光度法测定布洛芬溶液的经皮释药量，可消除鼠皮溶出物的干扰。方法简便、快速、准确。布洛芬的平均回收率为９９．９４％，ＲＳＤ＝０．１８５％。Second order derivative spectrophotometry of transdermic permeability of ibuprofen liquid could eliminate the disturbance of dissolution of mouse's skin.This method was simple,rapid and precise.The average recovery of ibuprofen was 99.94%,RSD=0.185%.

关 键 词：布洛芬 二阶导数 分光光度法 经皮渗透 

分 类 号：R971.1[医药卫生—药品]