注射毒品者丙型肝炎病毒感染率及其危险因素研究  

Study of hepatitis C virus infection rate and its risk factors among injecting drug users in Beijing, China

作　　者：张敏英[1] 吴尊友[2] 明中强[2] 顾淼[2] 武俊龙[2] 米国栋[2] 

机构地区：[1]天津医科大学流行病学教研室,天津300070 [2]中国疾病预防控制中心艾滋病性病预防控制中心,北京100020

出　　处：《疾病控制杂志》2006年第2期139-141,共3页Chinese Journal of Disease Control and Prevention

摘　　要：目的了解北京市注射毒品者HCV感染状况及其危险因素，评估注射毒品人群中HIV感染高危行为流行水平，为制定预防和控制艾滋病的策略和措施提供科学依据。方法选择北京市强制戒毒所新收治的注射毒品者和自社区招募的注射毒品者作为研究对象，采用问卷调查的方法进行资料的收集，采集静脉血5ml，实验室检测HCV抗体。资料的分析采用单因素分析、多因素分析。结果北京市注射毒品者的HIV感染率和HCV感染率分别为7．33％和52．59％。多因素分析结果表明：HCV感染的危险因素有在强制戒毒所（OR=2．37，95％CI1．55～5．72）、非北京市户籍（OR=1．94，95％CI为1．05～3．45）和注射次数≥100次（OR=2．60，95％CI为1．54-7．03）。结论北京市注射毒品人群HCV的感染率高达52．59％，标志着HIV感染高危行为在这一人群中广泛存在，应立即采取相应措施控制HIV和HCV感染的进一步扩散。Objective To assess the HCV epidemic situation and find out its risk factors among injecting drug users （IDUs） in Beijing, in order to provide scientific basis for making the AIDS preventive and control measure. Methods The target populations included IDUs both from the forcible detoxification center and community. Questionnaire was employed in the study. Gathered vein blood 5 ml, tested HCV antibody in the laboratory. Data was analyzed using univariate and multivariate logistic regression. Results The infection rates of HIV and HCV were 7.33 % , 52.59 % respectively. Multivariate logistic regression analysis suggested risk factors of HCV infection were being arrested into forcible detoxification center, total injecting times more than one hundred and being immigrant, and their corresponding odds ratio （ OR ） with 95 % CI were 2.37 （ 1.55- 5.72）, 2.60 （ 1.54- 7.03） and 1.94 （ 1.05- 3.45） respectively . Conclusions The infection rate of HCV was 52.59% among injecting drug users in Beijing, which showed that HIV risk behaviors were popular among these population.

关 键 词：肝炎 丙型 毒品 注射 危险因素 

分 类 号：R512.64[医药卫生—内科学] R575.1[医药卫生—临床医学]