长、短期驻舰对直升机机组人员血浆β-EP,ACTH和CRH的影响  

Effect of long and short-term voyage on plasma levels of β-EP, ACTH and CRH in carrier-based helicopter pilots

作　　者：张慧[1] 沈俊[1] 戴永红[2] 汪家春[1] 王昊[1] 马晓艳[2] 陈林[2] 

机构地区：[1]海军医学研究所航空医学研究室 [2]海军92635部队

出　　处：《中华航海医学与高气压医学杂志》2006年第1期10-11,共2页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

基　　金：全军后勤"十五"科研计划课题(013307)

摘　　要：目的探讨直升机机组人员长期、短期驻舰海上航行前后血浆POMC-源性肽β-EP,ACTH 及调节因子CRH含量变化的特点,为海上航行期间航空医学保障提供依据。方法对参加为期7 d(短期)驻舰和132 d(长期)驻舰各6名直升机机组人员,采用放射免疫法测定航行前后血浆β-EP,ACTH 和CRH的含量。结果短期海上航行后血浆β-EP,ACTH较航行前有显著性升高(P<0．05),但CRH 无显著性变化(P>0.05);而长期海上航行后血浆β-EP,ACTH,CRH均呈显著性下降(P<0．01或 <0．05)。结论驻舰海上航行可导致直升机机组人员血浆POMC-源性肽β-EP,ACTH及CRH含量发生变化,且航程对血浆β-EP,ACTH和CRH有影响。Objective To investigate changes of plasma levels of β-EP, ACTH and CRH in carrierbased helicopter pilots before and after short-term voyage and long-term voyage. Methods Six pilots went on 7 days voyage （short-term） and other six pilots on 132 days voyage （long-term）. Plasma levels of β-EP, ACTH and CRH were measured in the piths by radioimmunoassay before and after voyage. Results After short-term voyage, the levels of β-EP, ACTH increased significantly than those before voyage （P 〈 0. 05 ）, but the level of CRH did not change;after long-term voyage the levels of β-EP, ACTH and CRH decreased significantly than those before voyage（P 〈0.05）. Conclusions Plasma β-EP,ACTH and CRH in cartier-based helicopter pilots could be influenced by both the short-term and long-term voyage, their changes were correlative to the length of voyage.

关 键 词：直升机飞行人员 短期远航 长期远航 POMC-源性肽 调节因子 

分 类 号：R83[医药卫生—航空、航天与航海医学] R85[医药卫生—临床医学]