加速溶剂提取法提取赤芍中的芍药苷  

Extraction of paeoniflorin in Radix Paeoniae rubra by accelerated solvent extraction

作　　者：王乾[1] 刘三康[1] 付春梅[1] 李章万[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2006年第2期184-186,共3页West China Journal of Pharmaceutical Sciences

摘　　要：目的探讨快速溶剂提取法提取芍药苷的可行性,比较该方法与超声提取法索氏提取法和亚临界水提取法的优越性。方法以芍药苷含量为指标,用单因素考察法对影响加速溶剂提取芍药苷的因素进行优化。结果优选出了加速溶剂提取法提取芍药苷的最佳条件,即以50%乙醇为溶剂,提取温度100℃,提取压力50 kg,流速0.7 ml.min-1,动态提取12 min,收集提取液8 ml。结论加速溶剂提取法可以快速、高效地提取芍药苷。OBJECTIVE To discuss the feasibility of the accelerated solvent extraction（ASE） for paeoniflofin. METHODS Different factors and levels were investigated by method of single factor. RESULTS The most favorable conditions of extraction process were as follows： the concentration of alcohol was 50%, the temperature was 100℃, the pressure was 50 kg, the velocity flow was 0.7 ml· min^-1, the extraction time was 12min, and the collected volume was 8 ml. CONCLUSION The ASE could extract paeoniflorin from Radix Paconiae rubra quickly and effectively.

关 键 词：赤芍 芍药苷 加速溶剂提取 

分 类 号：R283[医药卫生—中药学]