孕妇肥胖对子代出生1个月内体格发育和瘦素浓度的影响  

Influence of Obese Pregnancy with Anthropometric Parameters and Leptin Levels of Offspring in the First Month of Life

作　　者：张晓[1] 夏光[1] 李爱斌[1] 

机构地区：[1]武汉大学人民医院儿科,湖北武汉430060

出　　处：《中国妇幼保健》2006年第7期944-945,共2页Maternal and Child Health Care of China

基　　金：湖北省计生委基金资助

摘　　要：目的:研究孕妇肥胖对子代出生1个月内体格发育和瘦素浓度的影响。方法:选择肥胖孕妇和正常体重孕妇各60人,比较她们的子代在出生后及满1个月时的体重、身高和血清瘦素,浓度瘦素检测使用双抗体夹心ELISA法。结果:①肥胖孕妇的瘦素浓度明显高于正常体重孕妇(P<0·01);②肥胖孕妇组子代出生体重和脐血瘦素浓度明显高于正常组(P<0·01);③肥胖孕妇组子代1个月的体重和血清瘦素浓度明显高于正常组(P<0·05)。结论:孕妇肥胖对子代出生后第一个月的体重和瘦素浓度均有明显的影响。Objective： To study the influence of obese pregnancy with anthropometric parameters and leptin levels of offspring in the first month of life. Methods： To select 80 obese and normal pregnancy respectively, then compare anthropometric parameters height, weight and leptin levels of their offspring in the first month of life; Leptin was examined by using a double - antibody with filling ELISA assay. Results： ① Serum leptin levels was significantly higher in obese pregnancy than in normal pregnancy （P 〈0. 01 ） ; ②Born weight and the cord blood leptin levels were significantly higher in offspring of obese pregnancy than that of normal pregnancy （ P 〈 0. 01 ） ;③ Weight and serum leptin levels in one month were significantly higher in offspring of obese pregnancy than that of normal pregnancy （P 〈 0. 01 ） . Conclusion： Obese significantly affect weight and leptin levels of women offspring in first month of life.

关 键 词：肥胖 孕妇 体格发育 瘦素 

分 类 号：R174[医药卫生—妇幼卫生保健]