深稀释温氧合血心停跳液持续灌注行心脏瓣膜手术  

Heart valve surgery under deep dilution with continuous warm oxygenated blood cardioplegia

作　　者：乔晨晖[1] 赵松[1] 郅兴义[1] 张明堪[1] 杨栋[1] 赵文增[1] 徐敬[1] 成向一[1] 

机构地区：[1]河南医科大学第一附属医院胸心外科

出　　处：《河南医科大学学报》1996年第3期48-50,共3页Journal of Henan Medical University

摘　　要：采用浅低温、深度血液稀释体外循环，温氧合血心停跳液持续灌注心肌保护，行心脏瓣膜手术２６例，经临床及动脉血气分析、心肌超微结构、血清［Ｋ＿＋］等指标观察，结果显示：温氧合血心停跳液持续灌注心肌保护方法使心脏自动复跳率达９２．３％。血气分析无缺氧及明显酸中毒，心肌超微结构未见明显异常改变，术后血流动力学稳定。开放主动脉前血清［Ｋ＿＋］较术前明显升高（Ｐ＜０．０５）。表明该体外循环技术和心肌保护方法应用于心脏瓣膜手术效果良好。heart valve operations were performed under deep dilution through cardiopulmonary bypass(CPB)with mild hypothermia and myocardial protection by continuous perfusion of warm oxygenated blood cardioplegia. The indices of clinical data,arterial blood gas analysis,myocardial ultrastructure,and potassium level in serum were observed.The results showed that the spontaneous resuscitation rate of the heart after continuous perfusion with warm oxygenated blood cardiopledgia was 92.3%. There was no anoxia and acidosis. There were no abnormal changes of myocardial ultrastructure. Postoperative hemodynamics was stable. The potassium level in serum before aortic de-clamping was higher than that of preoperation (P<0.05).The results indicate that the technique of CPB and the method of myocardial protection can be used in the heart valve operation with satisfactory result.

关 键 词：血液稀释 体外循环 心停跳液 心脏膜手术 

分 类 号：R654.2[医药卫生—外科学]