猪囊尾蚴细胞疫苗对仔猪先天性和获得性免疫的作用  

Effect of Cysticercus Cellulosae Cell Vaccine on Congenital and Acquired Immunity in Piglets

作　　者：马春艳[1] 张京[1] 张中庸[1] 李靓茹 

机构地区：[1]天津实验动物中心,天津300381

出　　处：《中国比较医学杂志》2006年第3期167-169,共3页Chinese Journal of Comparative Medicine

摘　　要：目的观察猪囊尾蚴细胞疫苗对妊娠母猪、具有母源抗体的仔猪和正常仔猪的影响。方法通过ELISA方法检测血清抗体,以确定疫苗对不同实验猪的免疫效果。结果妊娠母猪产生的抗体可达到1∶20480,并使仔猪获得的母源抗体接近有效抗体滴度1∶2560,出生后适时追加免疫,短期内即可产生较高抗体水平。结论猪囊尾蚴细胞疫苗免疫怀孕母猪后,母猪体内产生的抗体可以传递给仔猪,使仔猪获得先天性免疫力,具备抵抗猪囊尾蚴虫卵的侵袭。免疫正常仔猪产生有效抗体时间较晚。Objective To assess the influence of cysticercus cellulosae cell vaccine on immunization in pregnant sows, piglets with maternal antibody and normal piglets, nothods To measure serum antibody by ELISA method and determine the immunized results of different experimental pigs. Results Antidody titer of pregant sows reached a titer of 1 ： 20480. Piglets possessed maternal antibody showed a near the effective titer 1：2560. Giving an additional immunization after birth at proper time, the antibody level can be further raised shortly. Conclusion The maternal antibody from pregnant sows immunized by Cysticerus cellulosae cell vaccine can be transmitted to piglets, making them possessing congenital immunity and resistant to invasion of Cysticercus cellulosae eggs, Immunization of normal piglets with the same vaccine induces an effective antibody level much slowly.

关 键 词：先天性免疫 母源抗体 猪囊尾蚴细胞疫苗 

分 类 号：R392[医药卫生—免疫学]