ICU病区耐甲氧西林金黄色葡萄球菌感染的流行病学调查  

Epidemiologic study of Meticill-resistant Staphylococcus aureus nosocomial infection in intensive care unit

作　　者：廖常贵[1] 韩志伟[1] 李晓红[2] 

机构地区：[1]内江市第一人民医院检验科,四川内江641000 [2]内江市第一人民医院医院感染管理科,四川内江641000

出　　处：《中国微生态学杂志》2006年第2期124-125,128,共3页Chinese Journal of Microecology

摘　　要：目的通过对ICU病区耐甲氧西林金黄色葡萄球菌（MRSA）感染进行流行病学调查,并经过耐药菌谱的分析,探讨临床分离菌株的同源性,为预防和控制医院感染提供参考.方法对2005年3月7日～3月29日ICU病区感染MRSA的10例患者及医院环境进行了流行病学调查分析.结果ICU病区MRSA的感染率为47.6%.且环境中空气、陪护人员手、医务人员等亦培养出MRSA,通过耐药谱分析显示细菌具有高度同源性.结论该次MRSA感染为局部暴发流行.医院必须加强室内外环境和空气监控,防止交叉感染,严格无菌侵入性操作和抗生素的使用原则,从而有效减少MRSA院内感染的发生.Objective To investigate the epidemic of Meticin-resistant Staphylococcus aureus（MRSA） in intensive care unit（ ICU）, and study the homogeneity of isolates by cluster analysis. The ways to preventing and treating this nosocomial infection. Methods The case histories from 10 in patients and environment of hospital who developed MRSA infection in ICU from Mar. 7 to Mar. 29, 2005, were studied retrospectively to find out the reason of the epidemia. Results The rate of MRSA infection was 47.6 % in ICU. MRSA could be found from the air, hands of accompanying persons, healthy care workers etc. The MRSA spectrum cultured from its treatment based on the sputum culture results was in accordance with that in its environment. Conclusions The MRSA infection was fulminate epidemiological at a certain ward. Intensifying environmental and airy monitoring inside and outside ICU, avoiding across infection, adopting aseptic courses in invasive procedures and keeping good utilization principles for antimicrobial drugs, decline nosocomial infection of the MRSA in ICU.

关 键 词：ICU 耐甲氧西林金黄色葡萄球菌 流行病学调查 

分 类 号：R378.11[医药卫生—病原生物学]