单纯性肥胖儿童临床与血脂成分分析  

Analysis of Clinical Symptoms and Blood Lipid Components in Simple Obesity Children

作　　者：阿依古丽[1] 陈永红[1] 杜军保[1] 

机构地区：[1]北京大学第一医院儿科,北京100034

出　　处：《实用儿科临床杂志》2006年第7期398-399,共2页Journal of Applied Clinical Pediatrics

基　　金：北京市科技计划项目资助(HO30930030530)

摘　　要：目的 对单纯性肥胖儿童临床与血脂成分进行分析，探讨单纯性肥胖儿童血脂代谢紊乱情况及临床意义。方法对50例2．5-16．0岁单纯性肥胖儿童与40例正常同年龄儿童的临床及血脂成分进行分析，应用生化分析仪检测血脂，包括三酰甘油（TG）、总胆固醇（TC）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）。应用超声诊断仪进行肝脏检查。结果 1．单纯性肥胖与对照组儿童年龄与身高无显著差异，而体质量与体质量指数（BMI）、血压（BP）两组间差异均有非常显著意义（P均〈0．001）。2．单纯性肥胖儿童血清TC、TG、LDL的浓度明显高于对照组，差异均有显著性（P均〈0．001），HDL浓度两组比较其差异无统计学意义（P〉0．05）。3．单纯性肥胖18例（36％）儿童肝脏B超示存在脂肪肝。结论单纯性肥胖儿童存在血脂代谢紊乱，血清TC、TG、LDL浓度均明显升高，预防动脉粥样硬化性心血管疾病必须从儿童时期开始。Objective To analyze blood lipid components in simple obesity children and to explore the effects of obesity in the lipid metabolism and its clinical significance. Methods A total of 90 children, including 50 simple obesity children（obesity group）and 40 normal children（control group）, were enrolled in this study. The age ranged from 2.5 to 16.0 years. Their blood lipid profiles of all the children were analyzed. The blood lipid profiles were examined by biochemical analysis,including triglyeride（TG）, total cbolesterol（TC）, low density lipoprotein（LDL） and high density lipoprotein（HDL） ,and the livers of all the children were analyzed. The blood lipid profiles were examined by ultrasonograph. Results 1. There were no significant differences in age and height in obesity group and control group, but there were significant differences in body mass index（BMI） and blood pressure（P〈 0. 001 ）. 2. The concentration of serum TC, TG, and LDL was significantly devated in obesity group（all P〈0. 001）. The differences of HDL concentration in patients and the controls were not obvious（P〉0.05） ,which had no statistical meaning. 3. Liver ultra sonogram showed that 18 cases had fatty liver （36%） in simple obesity children. Conclusions Metabolic disorder of blood lipid is present in simple obesity children, who have a tendency to get fatty liver. LDL is markedly elevated in obesity group. Arteriosclerotic cardiovascular disease should be prevented at earlier period of childhood.

关 键 词：肥胖症 血脂 儿童 

分 类 号：R723.14[医药卫生—儿科]