液基超薄细胞技术及TBS系统检测2635例宫颈涂片的临床分析  

Clinical analysis of 2635 cervical smear using thinprep cytologic test and the Bethesda system

作　　者：邹倩[1] 濮德敏[1] 周利平[1] 杜鹃[1] 张惠萍[1] 王忠琴[1] 卢运萍[1] 

机构地区：[1]华中科技大学附属同济医院,湖北武汉430030

出　　处：《中国实用妇科与产科杂志》2006年第4期268-270,共3页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的对液基超薄细胞技术(thinprepcytologictest,TCT)和Bethesda系统(TBS)在宫颈病变诊断中的临床应用价值进行评价。方法2004年12月至2005年5月对在同济医院妇产科门诊就诊的2635例患者行TCT检查和TBS细胞学分类诊断,对TCT检查发现异常的患者进行阴道镜病理检查和HCⅡHPV检测。结果2635例涂片中检出异常涂片493例(18.71%),其中不典型鳞状细胞(ASCUS)166例(6.30%),低度鳞状上皮内病变(LSIL)94例(3.57%),高度鳞状上皮内病变(HSIL)14例(0.53%),鳞状细胞癌(SCC)1例(0.04%),子宫内膜腺癌1例(0.04%),HPV感染105例(3.98%)。TCT与阴道镜病理检查和HCⅡ检测的符合率分别为81.18%、70.48%。结论TCT技术结合TBS应用于宫颈细胞涂片配合HPVDNA检测和阴道镜活检,是筛查和诊断子宫颈癌前病变的可靠手段。Objective To evaluate the clinical value of thinprep cytologic test（TCT） and the Bethesda system（TBS） for the diagnosis of early cervical diseases. Methods A total of 2635 patients in our hospital had been examined by TCT and TBS from December 2004 to May 2005. The abnormal cases which had been selected by TCT were detected by colposcopical pathological examination and Hybrid Capture H HPV testing. Results We found 493 （ 18. 71% ） abnormal smears out of 2635 cases, in which atypical squamous cell of undetermined significance （ASCUS） 166 cases （6. 30% ）, low grade squamous intraepithelial lesion（LSIL） 94 cases （3. 57% ）, high grade squamous intraepithefial lesion （HSIL） 14 cases（0. 53% ）, squamous cell carcinoma 1 case（0. 04% ）, adenocarcinoma endometrium 1 case（0. 04% ）, HPV infection 105 cases （3.98%）. The rates of coordinance with pathological results of colposcopy and HC H were 81.18% and 70. 48% respectively. Conclusion TCT and TBS,sometimes combined with the colposcopy and HPV DNA test,may be a reliable method to screen and diagnose the precancerosis of cervix.

关 键 词：宫颈涂片 液基超薄细胞技术 TBS系统 人乳头病毒 

分 类 号：R71[医药卫生—妇产科学]