剖宫产术后不同抗菌药物预防用药方案的成本-效果分析  

Post-operative Preventive Medication of Antibacterials for Patients with Uterine-incision Delivery:Cost-effectiveness Analysis

作　　者：欧定宏[1] 韦湘洲[1] 黄婉群[1] 

机构地区：[1]广州市妇婴医院药剂科,广州市510180

出　　处：《中国药房》2006年第7期508-509,共2页China Pharmacy

摘　　要：目的:评价4种抗菌药物用药方案预防剖宫产术后感染的成本-效果。方法:对我院1066例产科剖宫产术后应用A(头孢哌酮钠/舒巴坦钠+甲硝唑)、B(氨苄西林钠/舒巴坦钠+甲硝唑)、C(头孢拉定+甲硝唑)、D(头孢哌酮钠/舒巴坦钠)4种方案预防感染,进行回顾性成本-效果分析。结果:4种方案成本分别为4954.13、4752.77、3870.16、3988.22元;有效率分别为98.5%、87.4%、84.6%、96.8%;成本-效果比分别为50.30、54.38、45.75、41.20;A、B、D方案相对于C方案的增量成本-效果比分别为77.98、315.22、9.68。结论:D方案预防剖宫产术后感染较为经济、合理。OBJECTIVE： To compare the cost effectiveness of 4 antibacterials in the prevention of post - operative infection in patients with uterine- incision delivery（UID） .METHODS： A total of 1 066 cases with UID were ascribed to receive cefoperazone sodium/sulbactam sodium ＋ arilin （therapy A）, ampicillin sodium/sulbactam sodium ＋ arilin（B）, cefradine ＋ arilin（C） and cefoperazone sodium/sulbactam sodium（D）, respectively for the prevention of infection. The cost effectiveness of the 4 groups was analyzed retrospectively. RESULTS： The costs of the 4 schemes were 4 954.13 yuan, 4 752.77 yuan, 3 870.16 yuan and 3 988.22 yuan, respectively; The effective rates were 98.5%, 87.4%, 84.6% and 96.8%, respectively; The cost-effectiveness ratios were 50.30, 54.38, 45.75 and 41.20, respectively ;The incremental cost - effectiveness ratios of scheme A, B and D were 77.98, 315.22 and 9,68, respectively as against scheme C. CONCLUSIONS： Scheme D is more economical and reasonable in the prevention of post- operative infection in patients with UID.

关 键 词：剖宫产手术 预防感染 抗菌药物 成本-效果分析 

分 类 号：R956[医药卫生—药学]